LINC02749

Summary

LINC02749 (long intergenic non-protein coding RNA 2749, HGNC:54268) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54268
Approved symbol	LINC02749
Name	long intergenic non-protein coding RNA 2749
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254480
Ensembl biotype	lncRNA
Entrez	100506082
RNAcentral	URS000075BE3C — lncRNA, 463 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000525365, ENST00000667222, ENST00000723521

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525365 — 2 exons

Exon	Start	End
ENSE00004045266	4187120	4187204
ENSE00004045268	4202259	4202669

Expression profiles

Bgee: expression breadth ubiquitous, 142 present calls, max score 83.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0582 / max 29.4178, expressed in 13 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
112770	0.0314	12
112769	0.0268	8

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.73	gold quality
oocyte	CL:0000023	75.21	gold quality
sperm	CL:0000019	73.87	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.77	gold quality
ganglionic eminence	UBERON:0004023	67.19	gold quality
secondary oocyte	CL:0000655	66.27	silver quality
right testis	UBERON:0004534	63.73	gold quality
left testis	UBERON:0004533	63.01	gold quality
right lobe of liver	UBERON:0001114	62.82	gold quality
left ovary	UBERON:0002119	62.28	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.19	gold quality
testis	UBERON:0000473	61.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.78	gold quality
gall bladder	UBERON:0002110	60.20	gold quality
mucosa of stomach	UBERON:0001199	59.81	gold quality
right ovary	UBERON:0002118	58.11	gold quality
ovary	UBERON:0000992	58.09	gold quality
monocyte	CL:0000576	57.58	gold quality
liver	UBERON:0002107	56.92	gold quality
islet of Langerhans	UBERON:0000006	56.82	gold quality
prostate gland	UBERON:0002367	56.38	gold quality
nucleus accumbens	UBERON:0001882	56.35	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
muscle of leg	UBERON:0001383	54.23	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
pancreas	UBERON:0001264	54.19	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
body of pancreas	UBERON:0001150	53.79	gold quality
endocervix	UBERON:0000458	53.78	gold quality
gastrocnemius	UBERON:0001388	53.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.