LINC02757

Summary

LINC02757 (long intergenic non-protein coding RNA 2757, HGNC:54277) is a long non-coding RNA gene on chromosome 11q13.5.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54277
Approved symbol	LINC02757
Name	long intergenic non-protein coding RNA 2757
Location	11q13.5
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255363
Ensembl biotype	lncRNA
Entrez	101928813
RNAcentral	URS00026A2466 — lncRNA, 1192 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000532413, ENST00000637683, ENST00000656117, ENST00000716191, ENST00000716192, ENST00000716193, ENST00000716194, ENST00000716195, ENST00000716196, ENST00000716197

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532413 — 2 exons

Exon	Start	End
ENSE00002146215	76628096	76628481
ENSE00002187154	76630191	76630363

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 81.06.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2987 / max 24.2329, expressed in 108 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
121396	0.1979	82
121395	0.1008	55

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.78	gold quality
sural nerve	UBERON:0015488	72.93	silver quality
monocyte	CL:0000576	71.42	gold quality
leukocyte	CL:0000738	70.43	gold quality
placenta	UBERON:0001987	67.92	gold quality
bone marrow cell	CL:0002092	67.55	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.18	gold quality
right lung	UBERON:0002167	63.14	gold quality
right coronary artery	UBERON:0001625	62.97	gold quality
ectocervix	UBERON:0012249	62.80	gold quality
adipose tissue	UBERON:0001013	62.51	gold quality
ganglionic eminence	UBERON:0004023	61.65	gold quality
bone marrow	UBERON:0002371	61.48	gold quality
lung	UBERON:0002048	61.29	gold quality
upper lobe of left lung	UBERON:0008952	61.02	gold quality
omental fat pad	UBERON:0010414	60.56	gold quality
spleen	UBERON:0002106	60.49	gold quality
descending thoracic aorta	UBERON:0002345	60.34	gold quality
left coronary artery	UBERON:0001626	60.19	gold quality
skeletal muscle tissue	UBERON:0001134	60.18	gold quality
endocervix	UBERON:0000458	59.71	gold quality
vermiform appendix	UBERON:0001154	59.30	gold quality
ventricular zone	UBERON:0003053	58.91	silver quality
thoracic aorta	UBERON:0001515	58.86	gold quality
smooth muscle tissue	UBERON:0001135	58.84	gold quality
urinary bladder	UBERON:0001255	58.72	gold quality
ascending aorta	UBERON:0001496	58.72	gold quality
mucosa of stomach	UBERON:0001199	58.09	gold quality
blood	UBERON:0000178	58.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.