LINC02770

Summary

LINC02770 (long intergenic non-protein coding RNA 2770, HGNC:54290) is a long non-coding RNA gene on chromosome 1q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54290
Approved symbol	LINC02770
Name	long intergenic non-protein coding RNA 2770
Location	1q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228215
Ensembl biotype	lncRNA
Entrez	107985457
RNAcentral	URS00026A1B97 — lncRNA, 2464 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000430776, ENST00000664489, ENST00000775265, ENST00000775266, ENST00000775267

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430776 — 6 exons

Exon	Start	End
ENSE00001608835	191964394	191964489
ENSE00001680123	191875495	191875700
ENSE00001686752	191965322	191965413
ENSE00001696584	191975971	191976084
ENSE00001793464	192009839	192011260
ENSE00003710593	191977239	191977359

Expression profiles

Bgee: expression breadth broad, 45 present calls, max score 76.60.

Top tissues by expression

164 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.60	gold quality
monocyte	CL:0000576	66.82	gold quality
leukocyte	CL:0000738	66.43	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.05	gold quality
lower lobe of lung	UBERON:0008949	61.44	silver quality
mucosa of paranasal sinus	UBERON:0005030	59.80	gold quality
ventricular zone	UBERON:0003053	58.90	gold quality
cortical plate	UBERON:0005343	58.18	gold quality
epithelium of nasopharynx	UBERON:0001951	55.74	gold quality
vena cava	UBERON:0004087	55.08	gold quality
buccal mucosa cell	CL:0002336	55.05	silver quality
jejunal mucosa	UBERON:0000399	54.33	gold quality
lateral globus pallidus	UBERON:0002476	54.16	gold quality
biceps brachii	UBERON:0001507	52.88	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	52.58	gold quality
right lobe of liver	UBERON:0001114	49.67	silver quality
amygdala	UBERON:0001876	49.36	gold quality
cerebellar vermis	UBERON:0004720	48.63	gold quality
subthalamic nucleus	UBERON:0001906	48.50	gold quality
islet of Langerhans	UBERON:0000006	48.43	silver quality
lateral nuclear group of thalamus	UBERON:0002736	48.26	gold quality
gall bladder	UBERON:0002110	48.22	gold quality
muscle of leg	UBERON:0001383	48.20	silver quality
substantia nigra pars reticulata	UBERON:0001966	47.87	gold quality
jejunum	UBERON:0002115	47.87	gold quality
cardia of stomach	UBERON:0001162	47.84	gold quality
dorsal plus ventral thalamus	UBERON:0001897	47.35	gold quality
liver	UBERON:0002107	46.86	gold quality
testis	UBERON:0000473	46.52	gold quality
body of tongue	UBERON:0011876	46.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.