LINC02774

Summary

LINC02774 (long intergenic non-protein coding RNA 2774, HGNC:27923) is a long non-coding RNA gene on chromosome 1q44.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27923
Approved symbol	LINC02774
Name	long intergenic non-protein coding RNA 2774
Location	1q44
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226828
Ensembl biotype	lncRNA
Entrez	339529
RNAcentral	URS000075BE3F — lncRNA, 1809 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 36 — 36 lncRNA

ENST00000440494, ENST00000652928, ENST00000806721, ENST00000806722, ENST00000806723, ENST00000806724, ENST00000806725, ENST00000806726, ENST00000806727, ENST00000806728, ENST00000806729, ENST00000806730, ENST00000806731, ENST00000806732, ENST00000806733, ENST00000806734, ENST00000806735, ENST00000806736, ENST00000806737, ENST00000806738, ENST00000806739, ENST00000806740, ENST00000806741, ENST00000806742, ENST00000806743, ENST00000806744, ENST00000806745, ENST00000806746, ENST00000806747, ENST00000806748, ENST00000806749, ENST00000806750, ENST00000806751, ENST00000806752, ENST00000806753, ENST00000806754

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440494 — 12 exons

Exon	Start	End
ENSE00001591471	244003383	244003500
ENSE00001596391	244010697	244010920
ENSE00001606522	244024966	244025069
ENSE00001634803	243978410	243978519
ENSE00001643108	244041427	244041555
ENSE00001684806	243917402	243917526
ENSE00001699653	244043423	244043549
ENSE00001735448	244045228	244045291
ENSE00001747796	244010021	244010092
ENSE00001763960	244005058	244005158
ENSE00001787621	244027236	244027434
ENSE00001806092	244046892	244047317

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 67.28.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.28	gold quality
superior frontal gyrus	UBERON:0002661	63.58	gold quality
ventricular zone	UBERON:0003053	62.74	gold quality
nucleus accumbens	UBERON:0001882	62.71	gold quality
cortical plate	UBERON:0005343	62.03	gold quality
putamen	UBERON:0001874	61.50	gold quality
caudate nucleus	UBERON:0001873	61.29	gold quality
prefrontal cortex	UBERON:0000451	60.80	gold quality
anterior cingulate cortex	UBERON:0009835	60.60	gold quality
frontal cortex	UBERON:0001870	60.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	60.50	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.44	gold quality
right frontal lobe	UBERON:0002810	60.27	gold quality
cerebral cortex	UBERON:0000956	59.92	gold quality
ganglionic eminence	UBERON:0004023	58.94	gold quality
amygdala	UBERON:0001876	57.27	gold quality
temporal lobe	UBERON:0001871	57.16	gold quality
brain	UBERON:0000955	57.12	gold quality
Ammon’s horn	UBERON:0001954	56.91	gold quality
primary visual cortex	UBERON:0002436	56.63	gold quality
monocyte	CL:0000576	53.44	silver quality
lymph node	UBERON:0000029	52.13	gold quality
blood	UBERON:0000178	51.55	gold quality
granulocyte	CL:0000094	51.08	silver quality
corpus callosum	UBERON:0002336	50.91	gold quality
islet of Langerhans	UBERON:0000006	50.71	gold quality
multicellular organism	UBERON:0000468	50.63	gold quality
hypothalamus	UBERON:0001898	49.89	gold quality
substantia nigra	UBERON:0002038	49.37	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.