LINC02853

Summary

LINC02853 (long intergenic non-protein coding RNA 2853, HGNC:54390) is a long non-coding RNA gene on chromosome 15q14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54390
Approved symbol	LINC02853
Name	long intergenic non-protein coding RNA 2853
Location	15q14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259245
Ensembl biotype	lncRNA
Entrez	100507480
RNAcentral	URS00026A278A — lncRNA, 685 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000560056, ENST00000668741, ENST00000820296, ENST00000820297, ENST00000820298, ENST00000820299, ENST00000820300, ENST00000820301, ENST00000820302, ENST00000820303, ENST00000820304, ENST00000820305

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000560056 — 2 exons

Exon	Start	End
ENSE00004226136	36049102	36049542
ENSE00004226142	36046005	36046285

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 94.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0077 / max 6.7645, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
145829	0.0051	2
145828	0.0026	2

Top tissues by expression

207 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	94.09	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.94	gold quality
left testis	UBERON:0004533	85.40	gold quality
right testis	UBERON:0004534	85.06	gold quality
testis	UBERON:0000473	82.23	gold quality
sural nerve	UBERON:0015488	69.03	gold quality
buccal mucosa cell	CL:0002336	62.31	silver quality
monocyte	CL:0000576	56.80	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
epithelial cell of pancreas	CL:0000083	53.03	gold quality
islet of Langerhans	UBERON:0000006	52.90	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.37	gold quality
hindlimb stylopod muscle	UBERON:0004252	50.35	gold quality
myocardium	UBERON:0002349	50.25	gold quality
deltoid	UBERON:0001476	49.77	gold quality
adult organism	UBERON:0007023	49.75	gold quality
prefrontal cortex	UBERON:0000451	49.53	gold quality
muscle of leg	UBERON:0001383	49.27	gold quality
calcaneal tendon	UBERON:0003701	48.99	silver quality
pancreas	UBERON:0001264	48.98	gold quality
gastrocnemius	UBERON:0001388	48.91	gold quality
ileal mucosa	UBERON:0000331	48.59	silver quality
tibialis anterior	UBERON:0001385	48.59	silver quality
right lobe of liver	UBERON:0001114	48.45	silver quality
quadriceps femoris	UBERON:0001377	48.19	gold quality
left coronary artery	UBERON:0001626	48.17	gold quality
left adrenal gland cortex	UBERON:0035825	47.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.