LINC02870

Summary

LINC02870 (long intergenic non-protein coding RNA 2870, HGNC:27275) is a long non-coding RNA gene on chromosome 10q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27275
Approved symbol	LINC02870
Name	long intergenic non-protein coding RNA 2870
Location	10q26.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA432J24.4
Ensembl gene	ENSG00000180066
Ensembl biotype	lncRNA
Entrez	170393
RNAcentral	URS0000CCE032 — lncRNA, 744 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000392630, ENST00000490765, ENST00000701813, ENST00000755549, ENST00000755550, ENST00000755551, ENST00000755552

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000392630 — 3 exons

Exon	Start	End
ENSE00003516685	132445696	132445779
ENSE00004104747	132447737	132449408
ENSE00004104748	132445154	132445278

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 65.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3565 / max 64.0063, expressed in 68 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
107720	0.2485	43
107721	0.0555	22
206065	0.0436	18
107719	0.0089	2

Top tissues by expression

201 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tendon of biceps brachii	UBERON:0008188	65.94	gold quality
tendon	UBERON:0000043	65.82	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.63	gold quality
bone marrow cell	CL:0002092	64.56	silver quality
vena cava	UBERON:0004087	63.54	gold quality
granulocyte	CL:0000094	56.43	gold quality
lymph node	UBERON:0000029	55.84	gold quality
lower lobe of lung	UBERON:0008949	55.62	silver quality
leukocyte	CL:0000738	54.41	gold quality
islet of Langerhans	UBERON:0000006	54.40	gold quality
nasal cavity epithelium	UBERON:0005384	53.69	gold quality
monocyte	CL:0000576	53.66	gold quality
buccal mucosa cell	CL:0002336	53.21	gold quality
mucosa of transverse colon	UBERON:0004991	53.07	gold quality
trabecular bone tissue	UBERON:0002483	52.87	gold quality
esophagus mucosa	UBERON:0002469	51.82	gold quality
vermiform appendix	UBERON:0001154	51.69	gold quality
cerebellar vermis	UBERON:0004720	51.47	gold quality
gastrocnemius	UBERON:0001388	51.40	gold quality
esophagus	UBERON:0001043	51.27	gold quality
gall bladder	UBERON:0002110	51.06	gold quality
blood	UBERON:0000178	50.72	gold quality
lower esophagus mucosa	UBERON:0035834	50.66	gold quality
pharyngeal mucosa	UBERON:0000355	50.12	gold quality
caecum	UBERON:0001153	49.79	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.78	gold quality
body of tongue	UBERON:0011876	49.18	gold quality
bone marrow	UBERON:0002371	49.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	48.23	gold quality
prefrontal cortex	UBERON:0000451	47.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.63

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progression. (PMID:36583796)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.