LINC02891

Summary

LINC02891 (long intergenic non-protein coding RNA 2891, HGNC:55221) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55221
Approved symbol	LINC02891
Name	long intergenic non-protein coding RNA 2891
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-RTN4R-1
Ensembl gene	ENSG00000249923
Ensembl biotype	lncRNA
Entrez	284865
RNAcentral	URS0000783C4D — lncRNA, 2228 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000506039, ENST00000824273, ENST00000824274, ENST00000824275, ENST00000824276, ENST00000824277, ENST00000824278, ENST00000824279, ENST00000824280, ENST00000824281, ENST00000824282

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506039 — 5 exons

Exon	Start	End
ENSE00002047108	20198729	20199251
ENSE00002081129	20200055	20201326
ENSE00004233296	20205609	20205679
ENSE00004233303	20204653	20205132
ENSE00004233310	20204333	20204499

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 74.20.

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	74.20	gold quality
right uterine tube	UBERON:0001302	70.70	gold quality
duodenum	UBERON:0002114	66.07	gold quality
pigmented layer of retina	UBERON:0001782	61.47	gold quality
endothelial cell	CL:0000115	61.21	gold quality
ganglionic eminence	UBERON:0004023	59.04	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.00	gold quality
mucosa of paranasal sinus	UBERON:0005030	55.66	gold quality
jejunal mucosa	UBERON:0000399	55.44	gold quality
germinal epithelium of ovary	UBERON:0001304	55.09	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.03	gold quality
cerebellar hemisphere	UBERON:0002245	53.82	gold quality
cerebellar cortex	UBERON:0002129	53.74	gold quality
cerebellum	UBERON:0002037	53.35	gold quality
vermiform appendix	UBERON:0001154	53.17	gold quality
spleen	UBERON:0002106	53.09	gold quality
tibia	UBERON:0000979	52.69	gold quality
mucosa of transverse colon	UBERON:0004991	51.68	gold quality
lateral globus pallidus	UBERON:0002476	51.66	gold quality
prefrontal cortex	UBERON:0000451	51.45	gold quality
calcaneal tendon	UBERON:0003701	50.76	silver quality
fallopian tube	UBERON:0003889	50.39	gold quality
seminal vesicle	UBERON:0000998	50.08	gold quality
monocyte	CL:0000576	48.78	silver quality
jejunum	UBERON:0002115	48.48	gold quality
biceps brachii	UBERON:0001507	48.39	gold quality
medial globus pallidus	UBERON:0002477	48.29	gold quality
globus pallidus	UBERON:0001875	48.17	gold quality
gall bladder	UBERON:0002110	48.17	silver quality
substantia nigra pars compacta	UBERON:0001965	47.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.