LINC02946

Summary

LINC02946 (long intergenic non-protein coding RNA 2946, HGNC:27680) is a long non-coding RNA gene on chromosome 2q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27680
Approved symbol	LINC02946
Name	long intergenic non-protein coding RNA 2946
Location	2q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RMEL1
Ensembl gene	ENSG00000287036
Ensembl biotype	lncRNA
Entrez	285000
RNAcentral	URS000075C0E9 — lncRNA, 1416 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000658366, ENST00000720509, ENST00000720510, ENST00000720511, ENST00000720512, ENST00000720513, ENST00000720514, ENST00000720515, ENST00000720516, ENST00000720517, ENST00000720518, ENST00000720519, ENST00000720520

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000658366 — 2 exons

Exon	Start	End
ENSE00004039304	105610328	105610766
ENSE00004039312	105600418	105601257

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 84.17.

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.98	gold quality
ganglionic eminence	UBERON:0004023	63.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.74	gold quality
duodenum	UBERON:0002114	55.70	gold quality
gall bladder	UBERON:0002110	54.72	gold quality
monocyte	CL:0000576	53.86	gold quality
cerebellum	UBERON:0002037	53.44	gold quality
cerebellar cortex	UBERON:0002129	53.35	gold quality
cerebellar hemisphere	UBERON:0002245	53.34	gold quality
prefrontal cortex	UBERON:0000451	52.72	gold quality
islet of Langerhans	UBERON:0000006	52.09	gold quality
right hemisphere of cerebellum	UBERON:0014890	51.91	gold quality
placenta	UBERON:0001987	51.78	gold quality
blood	UBERON:0000178	51.48	silver quality
cortex of kidney	UBERON:0001225	51.33	silver quality
right uterine tube	UBERON:0001302	50.70	gold quality
bone marrow	UBERON:0002371	49.68	silver quality
pancreas	UBERON:0001264	49.64	gold quality
liver	UBERON:0002107	49.56	silver quality
adult mammalian kidney	UBERON:0000082	49.17	gold quality
transverse colon	UBERON:0001157	48.48	gold quality
body of pancreas	UBERON:0001150	48.47	gold quality
rectum	UBERON:0001052	48.15	gold quality
colon	UBERON:0001155	48.15	gold quality
intestine	UBERON:0000160	48.04	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.02	gold quality
small intestine	UBERON:0002108	47.53	gold quality
muscle of leg	UBERON:0001383	47.34	gold quality
frontal cortex	UBERON:0001870	47.24	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.