LINGO1-AS2

Summary

LINGO1-AS2 (LINGO1 antisense RNA 2, HGNC:51423) is a long non-coding RNA gene on chromosome 15q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51423
Approved symbol	LINGO1-AS2
Name	LINGO1 antisense RNA 2
Location	15q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259281
Ensembl biotype	lncRNA
Entrez	101929478
RNAcentral	URS000075B4F1 — lncRNA, 678 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000557799, ENST00000726053, ENST00000726054, ENST00000726055

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000557799 — 3 exons

Exon	Start	End
ENSE00002562965	77667671	77668074
ENSE00002569032	77666960	77667086
ENSE00004050216	77660044	77660183

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 82.39.

Top tissues by expression

172 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	82.39	gold quality
left testis	UBERON:0004533	77.71	gold quality
right testis	UBERON:0004534	76.32	gold quality
testis	UBERON:0000473	74.47	gold quality
oocyte	CL:0000023	65.20	gold quality
parotid gland	UBERON:0001831	63.82	gold quality
cortical plate	UBERON:0005343	62.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.78	gold quality
vena cava	UBERON:0004087	54.69	gold quality
decidua	UBERON:0002450	53.68	gold quality
skin of leg	UBERON:0001511	53.29	gold quality
skin of abdomen	UBERON:0001416	53.24	gold quality
prefrontal cortex	UBERON:0000451	52.91	gold quality
endothelial cell	CL:0000115	52.90	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.75	gold quality
Brodmann (1909) area 46	UBERON:0006483	50.30	gold quality
skeletal muscle tissue	UBERON:0001134	48.33	gold quality
gastrocnemius	UBERON:0001388	48.06	gold quality
biceps brachii	UBERON:0001507	47.86	gold quality
bronchial epithelial cell	CL:0002328	47.22	gold quality
zone of skin	UBERON:0000014	47.13	gold quality
bronchus	UBERON:0002185	46.88	gold quality
adult organism	UBERON:0007023	46.71	silver quality
tibial nerve	UBERON:0001323	46.28	gold quality
anatomical system	UBERON:0000467	45.81	gold quality
material anatomical entity	UBERON:0000465	45.54	gold quality
tendon of biceps brachii	UBERON:0008188	45.53	gold quality
multicellular organism	UBERON:0000468	45.44	gold quality
deltoid	UBERON:0001476	45.24	gold quality
liver	UBERON:0002107	45.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.