LIRIL2R

Summary

LIRIL2R (lincRNA regulator of IL2RA, HGNC:56638) is a long non-coding RNA gene on chromosome 6p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56638
Approved symbol	LIRIL2R
Name	lincRNA regulator of IL2RA
Location	6p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285578
Ensembl biotype	lncRNA
Entrez	105374869
RNAcentral	URS0002A3F397 — lncRNA, 2687 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000649453, ENST00000784400, ENST00000784401, ENST00000784402, ENST00000784403, ENST00000784404

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000649453 — 3 exons

Exon	Start	End
ENSE00004159090	184506	186899
ENSE00004159092	184140	184371
ENSE00004159097	179289	179349

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 88.89.

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	88.89	gold quality
middle temporal gyrus	UBERON:0002771	88.24	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.97	gold quality
sperm	CL:0000019	86.91	gold quality
Brodmann (1909) area 23	UBERON:0013554	85.25	gold quality
pancreatic ductal cell	CL:0002079	79.94	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.89	gold quality
buccal mucosa cell	CL:0002336	77.27	gold quality
primary visual cortex	UBERON:0002436	76.52	gold quality
cerebellar vermis	UBERON:0004720	74.09	gold quality
occipital lobe	UBERON:0002021	72.90	gold quality
epithelial cell of pancreas	CL:0000083	71.73	gold quality
bone marrow	UBERON:0002371	71.32	gold quality
prefrontal cortex	UBERON:0000451	70.89	gold quality
entorhinal cortex	UBERON:0002728	70.81	gold quality
lateral nuclear group of thalamus	UBERON:0002736	70.34	gold quality
kidney epithelium	UBERON:0004819	70.34	gold quality
frontal cortex	UBERON:0001870	70.08	gold quality
right frontal lobe	UBERON:0002810	69.92	gold quality
lateral globus pallidus	UBERON:0002476	69.52	gold quality
neocortex	UBERON:0001950	69.47	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.09	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.99	gold quality
superior frontal gyrus	UBERON:0002661	68.57	gold quality
cerebral cortex	UBERON:0000956	68.43	gold quality
cardiac muscle of right atrium	UBERON:0003379	68.11	gold quality
left ventricle myocardium	UBERON:0006566	67.68	gold quality
cardiac atrium	UBERON:0002081	67.33	gold quality
cortical plate	UBERON:0005343	66.73	gold quality
anterior cingulate cortex	UBERON:0009835	66.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.