LIX1-AS1

Summary

LIX1-AS1 (LIX1 and RIOK2 antisense RNA 1, HGNC:52976) is a long non-coding RNA gene on chromosome 5q15.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52976
Approved symbol	LIX1-AS1
Name	LIX1 and RIOK2 antisense RNA 1
Location	5q15
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251513
Ensembl biotype	lncRNA
Entrez	101926893
RNAcentral	URS00026A1A64 — lncRNA, 1534 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000504578, ENST00000750789, ENST00000834814

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504578 — 7 exons

Exon	Start	End
ENSE00002030820	97183008	97183240
ENSE00002067780	97103026	97103094
ENSE00002068554	97431744	97431900
ENSE00002070434	97183505	97183669
ENSE00002075036	97436553	97437217
ENSE00002075795	97089075	97089204
ENSE00002085885	97101759	97102132

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 78.55.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.55	silver quality
granulocyte	CL:0000094	67.90	gold quality
lymph node	UBERON:0000029	64.03	gold quality
bone marrow cell	CL:0002092	63.44	silver quality
ganglionic eminence	UBERON:0004023	60.48	silver quality
blood	UBERON:0000178	59.11	gold quality
ventricular zone	UBERON:0003053	58.77	silver quality
bone marrow	UBERON:0002371	58.38	gold quality
cerebellum	UBERON:0002037	58.13	gold quality
tonsil	UBERON:0002372	56.98	gold quality
leukocyte	CL:0000738	56.61	gold quality
spleen	UBERON:0002106	55.49	gold quality
liver	UBERON:0002107	55.23	silver quality
monocyte	CL:0000576	53.76	silver quality
vermiform appendix	UBERON:0001154	52.58	gold quality
prefrontal cortex	UBERON:0000451	51.49	gold quality
urinary bladder	UBERON:0001255	51.02	gold quality
frontal cortex	UBERON:0001870	50.23	gold quality
calcaneal tendon	UBERON:0003701	49.36	silver quality
anterior cingulate cortex	UBERON:0009835	49.30	gold quality
myometrium	UBERON:0001296	48.19	silver quality
corpus callosum	UBERON:0002336	48.04	silver quality
multicellular organism	UBERON:0000468	47.83	gold quality
cortex of kidney	UBERON:0001225	47.27	gold quality
islet of Langerhans	UBERON:0000006	47.15	silver quality
small intestine	UBERON:0002108	46.97	gold quality
small intestine Peyer’s patch	UBERON:0003454	46.94	gold quality
gall bladder	UBERON:0002110	46.88	gold quality
cerebral cortex	UBERON:0000956	46.62	gold quality
metanephros cortex	UBERON:0010533	46.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.