LIX1L-AS1

Summary

LIX1L-AS1 (LIX1L antisense RNA 1, HGNC:41210) is a long non-coding RNA gene on chromosome 1q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41210
Approved symbol	LIX1L-AS1
Name	LIX1L antisense RNA 1
Location	1q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234222
Ensembl biotype	lncRNA
Entrez	105371260
RNAcentral	URS0000BC45C1 — lncRNA, 614 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000366105, ENST00000412239, ENST00000421764, ENST00000437207, ENST00000437797, ENST00000447686, ENST00000448561, ENST00000595494, ENST00000595518, ENST00000596355, ENST00000597144, ENST00000598103, ENST00000598354, ENST00000599147, ENST00000599469, ENST00000599626, ENST00000600340, ENST00000601726, ENST00000630257, ENST00000840614

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000366105 — 2 exons

Exon	Start	End
ENSE00001656245	145941905	145942249
ENSE00001733191	145941196	145941227

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 87.05.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 6.7382 / max 108.1525, expressed in 1432 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4956	6.7173	1432
4955	0.0209	3

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.05	gold quality
testis	UBERON:0000473	81.74	gold quality
left testis	UBERON:0004533	81.45	gold quality
right testis	UBERON:0004534	81.42	gold quality
sural nerve	UBERON:0015488	79.38	gold quality
corpus callosum	UBERON:0002336	78.49	gold quality
gastrocnemius	UBERON:0001388	76.23	gold quality
blood	UBERON:0000178	76.11	gold quality
muscle of leg	UBERON:0001383	76.01	gold quality
monocyte	CL:0000576	75.86	gold quality
left ovary	UBERON:0002119	75.59	gold quality
leukocyte	CL:0000738	75.30	gold quality
ovary	UBERON:0000992	74.90	gold quality
bone marrow cell	CL:0002092	74.72	gold quality
lower esophagus mucosa	UBERON:0035834	74.64	gold quality
calcaneal tendon	UBERON:0003701	74.61	gold quality
right ovary	UBERON:0002118	74.51	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.10	gold quality
bone marrow	UBERON:0002371	73.73	gold quality
body of uterus	UBERON:0009853	73.48	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.45	gold quality
skeletal muscle tissue	UBERON:0001134	72.65	gold quality
granulocyte	CL:0000094	72.57	gold quality
lymph node	UBERON:0000029	72.38	gold quality
right uterine tube	UBERON:0001302	72.01	gold quality
tibial nerve	UBERON:0001323	71.96	gold quality
muscle tissue	UBERON:0002385	71.85	gold quality
mucosa of stomach	UBERON:0001199	71.73	gold quality
myometrium	UBERON:0001296	71.73	gold quality
pituitary gland	UBERON:0000007	71.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.