LMNB1-DT

Summary

LMNB1-DT (LMNB1 divergent transcript, HGNC:53089) is a long non-coding RNA gene on chromosome 5q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53089
Approved symbol	LMNB1-DT
Name	LMNB1 divergent transcript
Location	5q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251072
Ensembl biotype	lncRNA
Entrez	102723557
RNAcentral	URS0000A76E6E — lncRNA, 935 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000509185, ENST00000815038, ENST00000815039, ENST00000815040, ENST00000815041, ENST00000815042

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509185 — 4 exons

Exon	Start	End
ENSE00002045525	126762365	126762451
ENSE00002055855	126755537	126755712
ENSE00002073171	126776295	126776486
ENSE00002682720	126751963	126752421

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 72.22.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8563 / max 342.6100, expressed in 227 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
63199	0.6388	162
63200	0.2175	74

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	72.22	silver quality
cortical plate	UBERON:0005343	71.32	gold quality
skeletal muscle tissue	UBERON:0001134	70.64	silver quality
bone marrow cell	CL:0002092	70.18	silver quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
liver	UBERON:0002107	65.75	silver quality
bone marrow	UBERON:0002371	59.81	gold quality
ganglionic eminence	UBERON:0004023	59.57	gold quality
monocyte	CL:0000576	54.06	gold quality
adult mammalian kidney	UBERON:0000082	53.31	gold quality
left testis	UBERON:0004533	52.76	gold quality
right testis	UBERON:0004534	52.68	gold quality
testis	UBERON:0000473	52.52	gold quality
lymph node	UBERON:0000029	52.06	gold quality
vermiform appendix	UBERON:0001154	50.91	gold quality
blood	UBERON:0000178	50.72	silver quality
duodenum	UBERON:0002114	50.38	gold quality
prefrontal cortex	UBERON:0000451	49.66	silver quality
adrenal gland	UBERON:0002369	49.65	silver quality
small intestine	UBERON:0002108	49.46	gold quality
body of pancreas	UBERON:0001150	48.14	silver quality
heart left ventricle	UBERON:0002084	47.92	gold quality
multicellular organism	UBERON:0000468	47.63	gold quality
superior frontal gyrus	UBERON:0002661	46.78	silver quality
kidney	UBERON:0002113	46.74	silver quality
placenta	UBERON:0001987	46.49	gold quality
heart	UBERON:0000948	46.25	silver quality
tibial artery	UBERON:0007610	46.06	silver quality
frontal cortex	UBERON:0001870	45.55	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.