LMX1A-AS2

Summary

LMX1A-AS2 (LMX1A antisense RNA 2, HGNC:40343) is a long non-coding RNA gene on chromosome 1q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40343
Approved symbol	LMX1A-AS2
Name	LMX1A antisense RNA 2
Location	1q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224702
Ensembl biotype	lncRNA
Entrez	105371561
RNAcentral	URS00004A38AF — lncRNA, 692 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000457106

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457106 — 3 exons

Exon	Start	End
ENSE00001736873	165212842	165213090
ENSE00001745794	165211236	165211337
ENSE00001789480	165210627	165210967

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 86.80.

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
islet of Langerhans	UBERON:0000006	86.80	gold quality
left ventricle myocardium	UBERON:0006566	81.60	gold quality
cardiac muscle of right atrium	UBERON:0003379	81.56	gold quality
kidney epithelium	UBERON:0004819	78.10	gold quality
sperm	CL:0000019	77.96	gold quality
epithelial cell of pancreas	CL:0000083	76.89	gold quality
pancreatic ductal cell	CL:0002079	75.22	silver quality
buccal mucosa cell	CL:0002336	74.16	silver quality
myocardium	UBERON:0002349	72.62	gold quality
tibialis anterior	UBERON:0001385	70.67	silver quality
sural nerve	UBERON:0015488	66.42	silver quality
upper arm skin	UBERON:0004263	65.36	gold quality
quadriceps femoris	UBERON:0001377	64.36	gold quality
cortex of kidney	UBERON:0001225	64.26	gold quality
vastus lateralis	UBERON:0001379	63.09	gold quality
left testis	UBERON:0004533	61.27	gold quality
right testis	UBERON:0004534	61.18	gold quality
epithelium of nasopharynx	UBERON:0001951	61.09	gold quality
deltoid	UBERON:0001476	60.37	gold quality
nasal cavity epithelium	UBERON:0005384	60.24	gold quality
pancreas	UBERON:0001264	60.23	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	59.77	gold quality
testis	UBERON:0000473	59.55	gold quality
adult mammalian kidney	UBERON:0000082	59.31	gold quality
caecum	UBERON:0001153	58.29	gold quality
lateral globus pallidus	UBERON:0002476	58.27	gold quality
cartilage tissue	UBERON:0002418	57.61	gold quality
ileal mucosa	UBERON:0000331	57.34	silver quality
subthalamic nucleus	UBERON:0001906	56.94	gold quality
vena cava	UBERON:0004087	56.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.