LNCDAT

Summary

LNCDAT (lncRNA divergent activator of TBXT, HGNC:54855) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54855
Approved symbol	LNCDAT
Name	lncRNA divergent activator of TBXT
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Aliases	YYLNCT
Ensembl gene	ENSG00000288638
Ensembl biotype	lncRNA
Entrez	116804915
RNAcentral	URS0001981274 — lncRNA, 1558 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000674611, ENST00000675059, ENST00000675188, ENST00000675446, ENST00000675788, ENST00000675895, ENST00000676186

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000674611 — 1 exons

Exon	Start	End
ENSE00003899253	166168014	166171172

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 52.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0821 / max 61.9758, expressed in 32 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
71152	0.0238	3
71156	0.0222	9
71153	0.0175	6
71155	0.0123	3
71154	0.0064	1

Top tissues by expression

52 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	52.68	silver quality
prefrontal cortex	UBERON:0000451	51.92	silver quality
pituitary gland	UBERON:0000007	51.19	gold quality
brain	UBERON:0000955	50.65	gold quality
blood	UBERON:0000178	50.47	gold quality
lymph node	UBERON:0000029	50.38	gold quality
tonsil	UBERON:0002372	49.05	gold quality
adenohypophysis	UBERON:0002196	48.85	gold quality
myometrium	UBERON:0001296	48.14	silver quality
muscle of leg	UBERON:0001383	47.85	gold quality
stomach	UBERON:0000945	47.68	gold quality
vermiform appendix	UBERON:0001154	47.29	silver quality
omental fat pad	UBERON:0010414	47.28	gold quality
adipose tissue	UBERON:0001013	47.25	gold quality
left coronary artery	UBERON:0001626	46.82	gold quality
placenta	UBERON:0001987	45.83	silver quality
gastrocnemius	UBERON:0001388	45.72	silver quality
esophagus mucosa	UBERON:0002469	45.37	gold quality
endometrium	UBERON:0001295	45.31	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	44.33	gold quality
lower esophagus muscularis layer	UBERON:0035833	44.15	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	44.00	gold quality
lower esophagus	UBERON:0013473	43.98	gold quality
esophagus	UBERON:0001043	43.89	gold quality
spleen	UBERON:0002106	43.68	silver quality
right atrium auricular region	UBERON:0006631	43.42	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.31	gold quality
tibial artery	UBERON:0007610	43.24	silver quality
zone of skin	UBERON:0000014	43.21	silver quality

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Signifying their developmental function, the key mesoderm specifier BRACHYURY (T) is accompanied by yylncT, which localizes to the active T locus during mesoderm commitment. (PMID:30554961)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.