LNCMB2

Summary

LNCMB2 (lncRNA MYC regulated medulloblastoma associated 2, HGNC:58925) is a long non-coding RNA gene on chromosome 8p11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58925
Approved symbol	LNCMB2
Name	lncRNA MYC regulated medulloblastoma associated 2
Location	8p11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253123
Ensembl biotype	lncRNA
Entrez	100507403

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 14 lncRNA, 1 TEC

ENST00000518765, ENST00000624599, ENST00000655057, ENST00000661295, ENST00000664078, ENST00000775655, ENST00000775656, ENST00000775657, ENST00000775658, ENST00000775659, ENST00000775660, ENST00000775661, ENST00000775662, ENST00000775663, ENST00000775664

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000518765 — 3 exons

Exon	Start	End
ENSE00004142714	37329774	37331166
ENSE00004142726	37331767	37331984
ENSE00004142733	37327364	37327935

Expression profiles

Bgee: expression breadth ubiquitous, 140 present calls, max score 80.28.

Top tissues by expression

230 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
popliteal artery	UBERON:0002250	80.28	gold quality
tibial artery	UBERON:0007610	80.26	gold quality
aorta	UBERON:0000947	74.20	gold quality
left coronary artery	UBERON:0001626	70.26	gold quality
ectocervix	UBERON:0012249	69.96	gold quality
bone marrow cell	CL:0002092	69.41	silver quality
coronary artery	UBERON:0001621	68.46	gold quality
ganglionic eminence	UBERON:0004023	67.34	gold quality
left uterine tube	UBERON:0001303	67.13	gold quality
thoracic aorta	UBERON:0001515	66.53	gold quality
ascending aorta	UBERON:0001496	66.43	gold quality
smooth muscle tissue	UBERON:0001135	65.59	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.20	gold quality
endocervix	UBERON:0000458	64.83	gold quality
uterine cervix	UBERON:0000002	64.36	gold quality
right coronary artery	UBERON:0001625	64.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.12	gold quality
descending thoracic aorta	UBERON:0002345	64.08	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	63.32	gold quality
body of uterus	UBERON:0009853	63.04	gold quality
omental fat pad	UBERON:0010414	62.56	gold quality
adipose tissue	UBERON:0001013	62.50	gold quality
peritoneum	UBERON:0002358	62.50	gold quality
colonic epithelium	UBERON:0000397	62.23	silver quality
rectum	UBERON:0001052	62.21	gold quality
adipose tissue of abdominal region	UBERON:0007808	62.15	gold quality
saphenous vein	UBERON:0007318	61.08	gold quality
gall bladder	UBERON:0002110	60.44	gold quality
left ovary	UBERON:0002119	60.20	gold quality
calcaneal tendon	UBERON:0003701	60.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.