LNCPOIR

Summary

LNCPOIR (lncRNA periodontal mesenchymal stem cell osteogenesis related, HGNC:54521) is a long non-coding RNA gene on chromosome 6q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54521
Approved symbol	LNCPOIR
Name	lncRNA periodontal mesenchymal stem cell osteogenesis related
Location	6q22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	POIR, lncRNA-POIR
Ensembl gene	ENSG00000232395
Ensembl biotype	lncRNA
Entrez	105377959
RNAcentral	URS00026A217A — lncRNA, 950 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000435802, ENST00000438522, ENST00000446358, ENST00000652989, ENST00000826447, ENST00000826448, ENST00000826449, ENST00000826450, ENST00000826451, ENST00000826452, ENST00000826453

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435802 — 4 exons

Exon	Start	End
ENSE00001764006	114535716	114536066
ENSE00003882012	114543793	114543921
ENSE00004237342	114545244	114545328
ENSE00004237345	114523443	114523692

Expression profiles

Bgee: expression breadth broad, 51 present calls, max score 91.03.

Top tissues by expression

51 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.03	gold quality
colonic epithelium	UBERON:0000397	75.93	gold quality
ganglionic eminence	UBERON:0004023	67.66	gold quality
sural nerve	UBERON:0015488	62.10	gold quality
prefrontal cortex	UBERON:0000451	61.83	gold quality
right testis	UBERON:0004534	61.80	gold quality
left testis	UBERON:0004533	61.73	gold quality
testis	UBERON:0000473	61.00	gold quality
multicellular organism	UBERON:0000468	55.98	gold quality
stomach	UBERON:0000945	55.85	gold quality
thoracic mammary gland	UBERON:0005200	55.54	gold quality
anterior cingulate cortex	UBERON:0009835	53.36	gold quality
corpus callosum	UBERON:0002336	52.97	gold quality
intestine	UBERON:0000160	52.52	gold quality
kidney	UBERON:0002113	52.52	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	51.44	gold quality
monocyte	CL:0000576	50.96	silver quality
muscle layer of sigmoid colon	UBERON:0035805	50.91	gold quality
substantia nigra	UBERON:0002038	50.51	gold quality
brain	UBERON:0000955	50.47	gold quality
small intestine Peyer’s patch	UBERON:0003454	50.40	gold quality
thyroid gland	UBERON:0002046	50.12	gold quality
adrenal tissue	UBERON:0018303	50.12	silver quality
Ammon’s horn	UBERON:0001954	49.83	gold quality
lung	UBERON:0002048	49.36	silver quality
placenta	UBERON:0001987	49.28	gold quality
blood	UBERON:0000178	49.16	silver quality
tibial nerve	UBERON:0001323	49.10	gold quality
putamen	UBERON:0001874	48.85	gold quality
skin of abdomen	UBERON:0001416	48.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.78

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• miR-182 overexpression in the inflammatory microenvironment resulted in an imbalance in the lncRNA-POIR-miR-182 regulatory network. (PMID:27512949)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.