LNCPRESS2

Summary

LNCPRESS2 (lncRNA p53 regulated and ESC associated 2, HGNC:52747) is a long non-coding RNA gene on chromosome 4q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52747
Approved symbol	LNCPRESS2
Name	lncRNA p53 regulated and ESC associated 2
Location	4q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249152
Ensembl biotype	lncRNA
Entrez	101929194
RNAcentral	URS00007E45B2 — lncRNA, 1225 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 33 — 33 lncRNA

ENST00000502518, ENST00000721183, ENST00000721184, ENST00000721185, ENST00000721186, ENST00000721187, ENST00000721188, ENST00000721189, ENST00000721190, ENST00000721191, ENST00000721192, ENST00000721193, ENST00000721194, ENST00000721195, ENST00000721196, ENST00000721197, ENST00000721198, ENST00000721199, ENST00000721200, ENST00000721201, ENST00000721202, ENST00000721203, ENST00000721204, ENST00000721205, ENST00000721206, ENST00000721207, ENST00000721208, ENST00000721209, ENST00000721210, ENST00000721211, ENST00000721212, ENST00000721213, ENST00000721214

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502518 — 2 exons

Exon	Start	End
ENSE00004040675	92268574	92269356
ENSE00004040682	92277050	92277229

Expression profiles

Bgee: expression breadth broad, 11 present calls, max score 58.03.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0393 / max 4.4566, expressed in 30 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
53170	0.0393	30

Top tissues by expression

11 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	58.03	gold quality
prefrontal cortex	UBERON:0000451	53.46	gold quality
cerebellar hemisphere	UBERON:0002245	43.30	silver quality
anterior cingulate cortex	UBERON:0009835	38.90	silver quality
caudate nucleus	UBERON:0001873	38.89	silver quality
esophagus mucosa	UBERON:0002469	38.82	silver quality
subcutaneous adipose tissue	UBERON:0002190	38.03	silver quality
substantia nigra	UBERON:0002038	37.72	silver quality
left ovary	UBERON:0002119	37.02	silver quality
testis	UBERON:0000473	36.84	silver quality
hypothalamus	UBERON:0001898	36.60	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.