LNROP

Summary

LNROP (long non-coding regulator of POU2F2, HGNC:55512) is a long non-coding RNA gene on chromosome 19q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55512
Approved symbol	LNROP
Name	long non-coding regulator of POU2F2
Location	19q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254887
Ensembl biotype	lncRNA
Entrez	100505622
RNAcentral	URS000075DBF1 — lncRNA, 701 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000527895, ENST00000531517, ENST00000559786, ENST00000715824, ENST00000715825

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527895 — 3 exons

Exon	Start	End
ENSE00002179878	42132905	42133028
ENSE00003987386	42136672	42137386
ENSE00003987387	42132555	42132761

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 82.09.

FANTOM5 (CAGE): breadth broad, TPM avg 1.7134 / max 61.6478, expressed in 491 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
176117	1.2641	425
176119	0.3594	174
176118	0.0767	30
176121	0.0133	1

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	82.09	gold quality
leukocyte	CL:0000738	81.77	gold quality
granulocyte	CL:0000094	78.70	gold quality
stromal cell of endometrium	CL:0002255	74.60	gold quality
sural nerve	UBERON:0015488	72.82	gold quality
vermiform appendix	UBERON:0001154	68.40	gold quality
lymph node	UBERON:0000029	68.34	gold quality
spleen	UBERON:0002106	67.81	gold quality
blood	UBERON:0000178	67.69	gold quality
bone marrow cell	CL:0002092	64.09	silver quality
pancreatic ductal cell	CL:0002079	62.54	silver quality
caecum	UBERON:0001153	62.31	gold quality
tonsil	UBERON:0002372	60.08	gold quality
ileal mucosa	UBERON:0000331	59.15	silver quality
endothelial cell	CL:0000115	58.57	silver quality
mucosa of transverse colon	UBERON:0004991	58.00	gold quality
gall bladder	UBERON:0002110	56.76	gold quality
bone marrow	UBERON:0002371	56.31	gold quality
small intestine Peyer’s patch	UBERON:0003454	55.12	gold quality
epithelial cell of pancreas	CL:0000083	54.96	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.85	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
tibialis anterior	UBERON:0001385	53.64	silver quality
small intestine	UBERON:0002108	53.55	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
right coronary artery	UBERON:0001625	53.32	gold quality
apex of heart	UBERON:0002098	52.12	gold quality
deltoid	UBERON:0001476	52.11	gold quality
islet of Langerhans	UBERON:0000006	51.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.