LNX1-AS1

Summary

LNX1-AS1 (LNX1 antisense RNA 1, HGNC:40345) is a long non-coding RNA gene on chromosome 4q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40345
Approved symbol	LNX1-AS1
Name	LNX1 antisense RNA 1
Location	4q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250930
Ensembl biotype	lncRNA
Entrez	100873939
RNAcentral	URS000075DCAF — lncRNA, 564 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000502373, ENST00000510785, ENST00000511989, ENST00000514364, ENST00000815256, ENST00000815257, ENST00000815258, ENST00000815259, ENST00000815260

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502373 — 2 exons

Exon	Start	End
ENSE00002037070	53496400	53496599
ENSE00002058302	53500417	53500502

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 94.18.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0074 / max 9.4728, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
47626	0.0074	3

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.18	gold quality
left testis	UBERON:0004533	84.04	gold quality
testis	UBERON:0000473	83.30	gold quality
right testis	UBERON:0004534	82.69	gold quality
colonic epithelium	UBERON:0000397	80.39	gold quality
lower esophagus mucosa	UBERON:0035834	69.87	gold quality
tonsil	UBERON:0002372	69.51	gold quality
corpus callosum	UBERON:0002336	68.67	gold quality
skeletal muscle tissue	UBERON:0001134	68.38	gold quality
sural nerve	UBERON:0015488	67.80	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.01	gold quality
primary visual cortex	UBERON:0002436	62.52	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.86	gold quality
uterine cervix	UBERON:0000002	60.56	gold quality
calcaneal tendon	UBERON:0003701	59.65	gold quality
endocervix	UBERON:0000458	58.21	gold quality
superior frontal gyrus	UBERON:0002661	58.09	gold quality
prefrontal cortex	UBERON:0000451	56.91	gold quality
kidney	UBERON:0002113	56.78	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.54	gold quality
right adrenal gland	UBERON:0001233	56.08	gold quality
islet of Langerhans	UBERON:0000006	55.79	gold quality
placenta	UBERON:0001987	55.68	gold quality
liver	UBERON:0002107	55.47	gold quality
skin of leg	UBERON:0001511	55.37	gold quality
monocyte	CL:0000576	55.36	gold quality
esophagus mucosa	UBERON:0002469	55.24	gold quality
esophagus	UBERON:0001043	54.12	gold quality
zone of skin	UBERON:0000014	54.07	gold quality
adult mammalian kidney	UBERON:0000082	53.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.