LOHAN2

Summary

LOHAN2 (lncRNA oncogene in head and neck cancer 2, HGNC:51371) is a long non-coding RNA gene on chromosome 16q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51371
Approved symbol	LOHAN2
Name	lncRNA oncogene in head and neck cancer 2
Location	16q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258779
Ensembl biotype	lncRNA
Entrez	100506172
RNAcentral	URS000075EA4C — lncRNA, 1328 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000554640, ENST00000555721, ENST00000557393, ENST00000561875, ENST00000562661, ENST00000562748, ENST00000641790, ENST00000655534, ENST00000656216, ENST00000662417, ENST00000663851, ENST00000664807, ENST00000665707, ENST00000666218, ENST00000666626, ENST00000667695, ENST00000668007, ENST00000669193, ENST00000669634, ENST00000669648, ENST00000670919, ENST00000670932, ENST00000671224, ENST00000736354, ENST00000736355, ENST00000763680, ENST00000763683

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554640 — 2 exons

Exon	Start	End
ENSE00002434658	73400139	73402480
ENSE00002479692	73387053	73387254

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 86.53.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0176 / max 16.2391, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155000	0.0176	3

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	86.53	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.41	silver quality
sural nerve	UBERON:0015488	76.05	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.92	gold quality
right testis	UBERON:0004534	68.40	gold quality
left testis	UBERON:0004533	68.05	gold quality
testis	UBERON:0000473	67.52	gold quality
sperm	CL:0000019	66.50	gold quality
calcaneal tendon	UBERON:0003701	64.99	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.46	gold quality
ganglionic eminence	UBERON:0004023	62.27	gold quality
ventricular zone	UBERON:0003053	61.69	gold quality
cortical plate	UBERON:0005343	59.73	gold quality
adrenal tissue	UBERON:0018303	59.31	gold quality
monocyte	CL:0000576	58.65	gold quality
leukocyte	CL:0000738	58.63	gold quality
tendon	UBERON:0000043	55.61	gold quality
epithelium of nasopharynx	UBERON:0001951	54.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.01	gold quality
adult organism	UBERON:0007023	53.56	silver quality
mucosa of stomach	UBERON:0001199	53.24	gold quality
muscle of leg	UBERON:0001383	53.00	gold quality
corpus callosum	UBERON:0002336	52.95	gold quality
stromal cell of endometrium	CL:0002255	52.94	silver quality
lower esophagus mucosa	UBERON:0035834	52.88	gold quality
lymph node	UBERON:0000029	52.86	gold quality
endothelial cell	CL:0000115	52.80	gold quality
granulocyte	CL:0000094	52.39	gold quality
right uterine tube	UBERON:0001302	52.38	gold quality
right lobe of liver	UBERON:0001114	52.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.