LOLI1

Summary

LOLI1 (lncRNA oncogene in liver cancer 1, HGNC:56775) is a long non-coding RNA gene on chromosome 3q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56775
Approved symbol	LOLI1
Name	lncRNA oncogene in liver cancer 1
Location	3q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241219
Ensembl biotype	lncRNA
Entrez	130932198
RNAcentral	URS0002853B65 — lncRNA, 1019 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000462010, ENST00000691778, ENST00000784518, ENST00000784519, ENST00000784520, ENST00000784521, ENST00000784522, ENST00000784523, ENST00000784524, ENST00000784525

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462010 — 3 exons

Exon	Start	End
ENSE00002340508	113058946	113059067
ENSE00004159334	113050910	113051705
ENSE00004159339	113063107	113063498

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 75.67.

Top tissues by expression

73 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
small intestine	UBERON:0002108	75.67	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.89	gold quality
ganglionic eminence	UBERON:0004023	59.95	gold quality
liver	UBERON:0002107	56.28	silver quality
skeletal muscle tissue	UBERON:0001134	52.46	silver quality
sural nerve	UBERON:0015488	52.04	silver quality
skin of abdomen	UBERON:0001416	51.78	gold quality
prefrontal cortex	UBERON:0000451	50.38	silver quality
blood	UBERON:0000178	50.11	silver quality
endometrium	UBERON:0001295	50.05	gold quality
lymph node	UBERON:0000029	49.68	silver quality
calcaneal tendon	UBERON:0003701	47.97	silver quality
monocyte	CL:0000576	47.73	silver quality
muscle of leg	UBERON:0001383	47.71	silver quality
adrenal tissue	UBERON:0018303	46.49	silver quality
islet of Langerhans	UBERON:0000006	46.40	silver quality
gastrocnemius	UBERON:0001388	46.29	silver quality
corpus callosum	UBERON:0002336	45.43	silver quality
gall bladder	UBERON:0002110	45.23	gold quality
placenta	UBERON:0001987	44.63	silver quality
adenohypophysis	UBERON:0002196	44.38	gold quality
tibial artery	UBERON:0007610	43.72	silver quality
heart	UBERON:0000948	43.55	silver quality
multicellular organism	UBERON:0000468	43.37	gold quality
saliva-secreting gland	UBERON:0001044	43.25	silver quality
tibial nerve	UBERON:0001323	43.25	silver quality
left adrenal gland	UBERON:0001234	43.08	silver quality
lung	UBERON:0002048	43.02	silver quality
smooth muscle tissue	UBERON:0001135	42.99	silver quality
cerebral cortex	UBERON:0000956	42.90	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.