LOXL2-AS1

Summary

LOXL2-AS1 (LOXL2 antisense RNA 1, HGNC:56648) is a long non-coding RNA gene on chromosome 8p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56648
Approved symbol	LOXL2-AS1
Name	LOXL2 antisense RNA 1
Location	8p21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC090197.1
Ensembl gene	ENSG00000253837
Ensembl biotype	lncRNA
Entrez	100507156
RNAcentral	URS000075CE0C — lncRNA, 4374 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 1 retained_intron, 1 lncRNA

ENST00000517420, ENST00000519692

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517420 — 2 exons

Exon	Start	End
ENSE00004098873	23336171	23337457
ENSE00004098874	23341026	23341572

Expression profiles

Bgee: expression breadth ubiquitous, 143 present calls, max score 69.46.

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	69.46	silver quality
buccal mucosa cell	CL:0002336	67.25	gold quality
stromal cell of endometrium	CL:0002255	66.37	gold quality
bone marrow cell	CL:0002092	66.13	silver quality
descending thoracic aorta	UBERON:0002345	64.36	gold quality
ascending aorta	UBERON:0001496	63.71	gold quality
thoracic aorta	UBERON:0001515	63.54	gold quality
islet of Langerhans	UBERON:0000006	61.83	gold quality
aorta	UBERON:0000947	61.46	gold quality
sural nerve	UBERON:0015488	60.54	silver quality
popliteal artery	UBERON:0002250	60.11	gold quality
tibial artery	UBERON:0007610	60.11	gold quality
apex of heart	UBERON:0002098	59.40	gold quality
right coronary artery	UBERON:0001625	57.77	gold quality
ganglionic eminence	UBERON:0004023	57.68	gold quality
left ovary	UBERON:0002119	57.19	gold quality
smooth muscle tissue	UBERON:0001135	57.03	gold quality
left coronary artery	UBERON:0001626	56.24	gold quality
body of uterus	UBERON:0009853	55.58	gold quality
pituitary gland	UBERON:0000007	55.54	gold quality
coronary artery	UBERON:0001621	55.48	gold quality
prefrontal cortex	UBERON:0000451	55.46	gold quality
right ovary	UBERON:0002118	55.32	gold quality
leukocyte	CL:0000738	55.24	silver quality
adenohypophysis	UBERON:0002196	54.92	gold quality
ovary	UBERON:0000992	54.84	gold quality
upper leg skin	UBERON:0004262	54.67	silver quality
vermiform appendix	UBERON:0001154	54.66	gold quality
calcaneal tendon	UBERON:0003701	54.52	gold quality
heart left ventricle	UBERON:0002084	54.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.