LPP-AS1

Summary

LPP-AS1 (LPP antisense RNA 1, HGNC:40346) is a long non-coding RNA gene on chromosome 3q28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40346
Approved symbol	LPP-AS1
Name	LPP antisense RNA 1
Location	3q28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224563
Ensembl biotype	lncRNA
Entrez	100873917
RNAcentral	URS000075D856 — lncRNA, 495 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000434996, ENST00000785237

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434996 — 2 exons

Exon	Start	End
ENSE00001686496	188562238	188562439
ENSE00004160880	188568375	188568895

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 92.76.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.76	gold quality
bone marrow cell	CL:0002092	70.34	silver quality
colonic epithelium	UBERON:0000397	69.56	gold quality
calcaneal tendon	UBERON:0003701	68.28	gold quality
lymph node	UBERON:0000029	67.68	gold quality
skeletal muscle tissue	UBERON:0001134	66.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.77	gold quality
sural nerve	UBERON:0015488	65.43	gold quality
right testis	UBERON:0004534	63.25	gold quality
left testis	UBERON:0004533	62.66	gold quality
testis	UBERON:0000473	62.17	gold quality
blood	UBERON:0000178	61.58	gold quality
liver	UBERON:0002107	61.41	gold quality
tonsil	UBERON:0002372	59.59	gold quality
urinary bladder	UBERON:0001255	59.35	gold quality
monocyte	CL:0000576	58.97	gold quality
corpus callosum	UBERON:0002336	57.58	gold quality
kidney	UBERON:0002113	57.42	gold quality
adrenal tissue	UBERON:0018303	56.62	gold quality
thoracic mammary gland	UBERON:0005200	55.56	gold quality
stomach	UBERON:0000945	55.46	gold quality
adult mammalian kidney	UBERON:0000082	55.42	gold quality
myometrium	UBERON:0001296	55.32	gold quality
cortex of kidney	UBERON:0001225	55.22	gold quality
muscle of leg	UBERON:0001383	55.10	gold quality
mucosa of stomach	UBERON:0001199	54.75	gold quality
vermiform appendix	UBERON:0001154	54.59	gold quality
placenta	UBERON:0001987	54.57	gold quality
islet of Langerhans	UBERON:0000006	53.98	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.