LRBA-AS1

Summary

LRBA-AS1 (LRBA antisense RNA 1, HGNC:58247) is a long non-coding RNA gene on chromosome 4q31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58247
Approved symbol	LRBA-AS1
Name	LRBA antisense RNA 1
Location	4q31.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249690
Ensembl biotype	lncRNA
Entrez	729558
RNAcentral	URS0000BC4431 — lncRNA, 1898 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000507934

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507934 — 2 exons

Exon	Start	End
ENSE00002030891	150579604	150581545
ENSE00002049191	150579089	150579355

Expression profiles

Bgee: expression breadth broad, 65 present calls, max score 69.84.

Top tissues by expression

65 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
uterine cervix	UBERON:0000002	69.84	gold quality
colonic epithelium	UBERON:0000397	69.22	silver quality
pancreas	UBERON:0001264	69.13	silver quality
bone marrow cell	CL:0002092	67.44	silver quality
muscle layer of sigmoid colon	UBERON:0035805	67.02	gold quality
colon	UBERON:0001155	64.05	gold quality
thoracic mammary gland	UBERON:0005200	63.69	silver quality
liver	UBERON:0002107	63.26	gold quality
intestine	UBERON:0000160	62.87	gold quality
tonsil	UBERON:0002372	61.48	silver quality
transverse colon	UBERON:0001157	61.04	gold quality
urinary bladder	UBERON:0001255	60.87	silver quality
thyroid gland	UBERON:0002046	60.57	silver quality
blood	UBERON:0000178	59.33	gold quality
smooth muscle tissue	UBERON:0001135	59.08	gold quality
kidney	UBERON:0002113	58.85	gold quality
calcaneal tendon	UBERON:0003701	58.25	gold quality
muscle of leg	UBERON:0001383	58.24	gold quality
small intestine	UBERON:0002108	58.18	gold quality
adult mammalian kidney	UBERON:0000082	57.67	gold quality
duodenum	UBERON:0002114	56.67	gold quality
myometrium	UBERON:0001296	56.50	silver quality
small intestine Peyer’s patch	UBERON:0003454	56.16	gold quality
ovary	UBERON:0000992	55.98	silver quality
adrenal tissue	UBERON:0018303	55.03	gold quality
adrenal gland	UBERON:0002369	54.52	gold quality
stomach	UBERON:0000945	53.92	gold quality
lung	UBERON:0002048	52.90	gold quality
multicellular organism	UBERON:0000468	52.87	gold quality
prostate gland	UBERON:0002367	51.49	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.