LRIG2-DT

Summary

LRIG2-DT (LRIG2 divergent transcript, HGNC:54312) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54312
Approved symbol	LRIG2-DT
Name	LRIG2 divergent transcript
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000238198
Ensembl biotype	lncRNA
Entrez	100996251
RNAcentral	URS000075EFE7 — lncRNA, 2456 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000421157, ENST00000765033, ENST00000765034, ENST00000765035, ENST00000765036, ENST00000765037

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421157 — 3 exons

Exon	Start	End
ENSE00001637133	113072939	113073113
ENSE00001644909	113011687	113013839
ENSE00001673641	113048423	113048561

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 67.02.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4348 / max 54.2742, expressed in 209 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13898	0.4348	209

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	67.02	silver quality
skeletal muscle tissue	UBERON:0001134	64.21	gold quality
bone marrow cell	CL:0002092	64.15	silver quality
cortical plate	UBERON:0005343	61.03	gold quality
ventricular zone	UBERON:0003053	60.83	gold quality
ganglionic eminence	UBERON:0004023	60.61	gold quality
islet of Langerhans	UBERON:0000006	59.89	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.89	gold quality
amygdala	UBERON:0001876	59.06	gold quality
temporal lobe	UBERON:0001871	59.00	gold quality
tonsil	UBERON:0002372	58.79	gold quality
endometrium	UBERON:0001295	58.43	gold quality
prefrontal cortex	UBERON:0000451	57.83	gold quality
nucleus accumbens	UBERON:0001882	57.67	gold quality
putamen	UBERON:0001874	57.49	gold quality
stromal cell of endometrium	CL:0002255	57.36	gold quality
caudate nucleus	UBERON:0001873	57.31	gold quality
substantia nigra	UBERON:0002038	57.18	gold quality
anterior cingulate cortex	UBERON:0009835	56.43	gold quality
adrenal tissue	UBERON:0018303	56.42	gold quality
Ammon’s horn	UBERON:0001954	56.35	gold quality
frontal cortex	UBERON:0001870	55.79	gold quality
bone marrow	UBERON:0002371	55.78	silver quality
liver	UBERON:0002107	55.72	gold quality
cerebral cortex	UBERON:0000956	55.49	gold quality
ovary	UBERON:0000992	55.16	gold quality
right atrium auricular region	UBERON:0006631	54.92	gold quality
brain	UBERON:0000955	54.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.72	gold quality
corpus callosum	UBERON:0002336	54.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.