LROMI1

Summary

LROMI1 (lncRNA regulator of macrophage immunity 1, HGNC:58488) is a long non-coding RNA gene on chromosome 17p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58488
Approved symbol	LROMI1
Name	lncRNA regulator of macrophage immunity 1
Location	17p12
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC022816.1
Ensembl gene	ENSG00000230647
Ensembl biotype	lncRNA
Entrez	107985080

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000436469, ENST00000655690, ENST00000700765, ENST00000822015, ENST00000822016, ENST00000822017, ENST00000822018, ENST00000822019, ENST00000822020, ENST00000822021, ENST00000822022, ENST00000822023, ENST00000822024, ENST00000822025, ENST00000822026, ENST00000822027, ENST00000822028, ENST00000822029, ENST00000822030, ENST00000822031

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436469 — 5 exons

Exon	Start	End
ENSE00001711591	14420657	14421026
ENSE00001720153	14374139	14374228
ENSE00001769896	14397062	14397172
ENSE00001773366	14382018	14382112
ENSE00002330873	14377284	14377421

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 81.25.

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.25	gold quality
liver	UBERON:0002107	74.84	gold quality
right lobe of liver	UBERON:0001114	73.66	gold quality
testis	UBERON:0000473	72.09	gold quality
skeletal muscle tissue	UBERON:0001134	65.61	gold quality
ventricular zone	UBERON:0003053	62.91	gold quality
ganglionic eminence	UBERON:0004023	59.88	gold quality
monocyte	CL:0000576	57.93	gold quality
endometrium	UBERON:0001295	55.22	silver quality
blood	UBERON:0000178	53.54	gold quality
muscle of leg	UBERON:0001383	53.40	gold quality
stromal cell of endometrium	CL:0002255	52.13	silver quality
multicellular organism	UBERON:0000468	51.50	gold quality
lymph node	UBERON:0000029	51.32	gold quality
body of uterus	UBERON:0009853	49.38	gold quality
vermiform appendix	UBERON:0001154	49.29	gold quality
islet of Langerhans	UBERON:0000006	48.89	gold quality
bone marrow	UBERON:0002371	48.73	silver quality
duodenum	UBERON:0002114	48.49	silver quality
adult mammalian kidney	UBERON:0000082	47.55	gold quality
gastrocnemius	UBERON:0001388	47.32	gold quality
placenta	UBERON:0001987	47.21	silver quality
urinary bladder	UBERON:0001255	47.15	gold quality
prefrontal cortex	UBERON:0000451	46.98	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	46.91	silver quality
heart	UBERON:0000948	46.84	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.43	gold quality
tibial artery	UBERON:0007610	45.42	gold quality
mucosa of transverse colon	UBERON:0004991	45.41	gold quality
lung	UBERON:0002048	45.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.