LRP1-AS

Summary

LRP1-AS (LRP1 antisense RNA, HGNC:51694) is a long non-coding RNA gene on chromosome 12q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51694
Approved symbol	LRP1-AS
Name	LRP1 antisense RNA
Location	12q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259125
Ensembl biotype	lncRNA
Entrez	105751187
RNAcentral	URS0000103821 — lncRNA, 645 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000554476, ENST00000555461

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554476 — 2 exons

Exon	Start	End
ENSE00002442548	57146490	57146723
ENSE00004107160	57147439	57147692

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 79.71.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	79.71	gold quality
sural nerve	UBERON:0015488	72.53	gold quality
monocyte	CL:0000576	69.08	gold quality
leukocyte	CL:0000738	68.50	gold quality
ganglionic eminence	UBERON:0004023	67.90	gold quality
right lung	UBERON:0002167	67.88	gold quality
skeletal muscle tissue	UBERON:0001134	67.62	gold quality
left ovary	UBERON:0002119	67.25	gold quality
right ovary	UBERON:0002118	67.18	gold quality
bone marrow cell	CL:0002092	66.72	silver quality
ovary	UBERON:0000992	66.64	gold quality
uterine cervix	UBERON:0000002	65.44	gold quality
calcaneal tendon	UBERON:0003701	64.81	gold quality
liver	UBERON:0002107	64.62	gold quality
urinary bladder	UBERON:0001255	64.12	gold quality
vagina	UBERON:0000996	64.05	gold quality
ectocervix	UBERON:0012249	64.00	gold quality
descending thoracic aorta	UBERON:0002345	63.35	gold quality
placenta	UBERON:0001987	62.77	gold quality
gall bladder	UBERON:0002110	62.52	gold quality
right lobe of liver	UBERON:0001114	62.29	gold quality
ascending aorta	UBERON:0001496	62.05	gold quality
left coronary artery	UBERON:0001626	62.02	gold quality
blood	UBERON:0000178	61.74	gold quality
thoracic aorta	UBERON:0001515	61.41	gold quality
corpus callosum	UBERON:0002336	61.40	gold quality
endocervix	UBERON:0000458	61.10	gold quality
lymph node	UBERON:0000029	61.05	gold quality
tonsil	UBERON:0002372	61.04	silver quality
bone marrow	UBERON:0002371	59.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.