LRP4-AS1

Summary

LRP4-AS1 (LRP4 antisense RNA 1, HGNC:44128) is a long non-coding RNA gene on chromosome 11p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44128
Approved symbol	LRP4-AS1
Name	LRP4 antisense RNA 1
Location	11p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247675
Ensembl biotype	lncRNA
Entrez	100507401
RNAcentral	URS00007599A9 — lncRNA, 1540 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000502049, ENST00000531719, ENST00000685112, ENST00000685514, ENST00000736458

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502049 — 3 exons

Exon	Start	End
ENSE00001987964	46846610	46846717
ENSE00002200969	46846412	46846499
ENSE00004069847	46873074	46874421

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 78.72.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6776 / max 34.2610, expressed in 402 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
206273	0.6776	402

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.72	gold quality
colonic epithelium	UBERON:0000397	76.24	gold quality
skin of leg	UBERON:0001511	72.45	gold quality
zone of skin	UBERON:0000014	72.12	gold quality
skin of abdomen	UBERON:0001416	71.38	gold quality
ventricular zone	UBERON:0003053	65.92	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.94	silver quality
testis	UBERON:0000473	63.50	gold quality
left testis	UBERON:0004533	63.42	gold quality
right testis	UBERON:0004534	62.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.57	gold quality
ganglionic eminence	UBERON:0004023	60.41	gold quality
cortical plate	UBERON:0005343	59.64	gold quality
stromal cell of endometrium	CL:0002255	59.60	gold quality
skeletal muscle tissue	UBERON:0001134	58.43	gold quality
endometrium	UBERON:0001295	57.64	gold quality
left adrenal gland	UBERON:0001234	56.33	gold quality
left adrenal gland cortex	UBERON:0035825	55.96	gold quality
adrenal gland	UBERON:0002369	55.58	gold quality
right adrenal gland	UBERON:0001233	55.46	gold quality
muscle tissue	UBERON:0002385	55.38	gold quality
anterior cingulate cortex	UBERON:0009835	55.20	gold quality
prefrontal cortex	UBERON:0000451	55.19	gold quality
right adrenal gland cortex	UBERON:0035827	54.82	gold quality
frontal cortex	UBERON:0001870	54.41	gold quality
calcaneal tendon	UBERON:0003701	54.33	silver quality
monocyte	CL:0000576	54.31	gold quality
left ovary	UBERON:0002119	54.25	gold quality
superior frontal gyrus	UBERON:0002661	54.12	gold quality
cerebral cortex	UBERON:0000956	53.99	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	15.95
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.