LRRC3-DT

Summary

LRRC3-DT (LRRC3 divergent transcript, HGNC:43636) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43636
Approved symbol	LRRC3-DT
Name	LRRC3 divergent transcript
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229356
Ensembl biotype	lncRNA
Entrez	100861510
RNAcentral	URS000075EBD0 — lncRNA, 800 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000426578, ENST00000843731

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426578 — 4 exons

Exon	Start	End
ENSE00001594641	44450986	44451289
ENSE00001630947	44451407	44451769
ENSE00001745110	44454977	44455052
ENSE00001789377	44455244	44455284

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 84.88.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0490 / max 4.6653, expressed in 21 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190752	0.0490	21

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.88	silver quality
right lobe of liver	UBERON:0001114	68.72	gold quality
muscle layer of sigmoid colon	UBERON:0035805	66.09	gold quality
liver	UBERON:0002107	64.60	gold quality
ventricular zone	UBERON:0003053	63.55	gold quality
cortical plate	UBERON:0005343	63.15	gold quality
ganglionic eminence	UBERON:0004023	62.94	gold quality
mucosa of stomach	UBERON:0001199	62.16	gold quality
fundus of stomach	UBERON:0001160	60.10	gold quality
gall bladder	UBERON:0002110	59.96	gold quality
colon	UBERON:0001155	59.68	gold quality
hypothalamus	UBERON:0001898	58.69	gold quality
intestine	UBERON:0000160	58.10	gold quality
body of stomach	UBERON:0001161	56.83	gold quality
stomach	UBERON:0000945	56.38	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	55.98	gold quality
left testis	UBERON:0004533	55.75	gold quality
testis	UBERON:0000473	55.42	gold quality
right testis	UBERON:0004534	55.12	gold quality
right adrenal gland cortex	UBERON:0035827	54.97	gold quality
urinary bladder	UBERON:0001255	54.31	gold quality
rectum	UBERON:0001052	53.98	gold quality
transverse colon	UBERON:0001157	53.74	gold quality
left ovary	UBERON:0002119	53.46	gold quality
monocyte	CL:0000576	53.29	silver quality
ovary	UBERON:0000992	53.02	gold quality
right ovary	UBERON:0002118	51.96	gold quality
lymph node	UBERON:0000029	51.82	gold quality
lower esophagus	UBERON:0013473	51.58	gold quality
lower esophagus muscularis layer	UBERON:0035833	51.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.