LRRC59-AS1

Summary

LRRC59-AS1 (LRRC59 antisense RNA 1, HGNC:58254) is a long non-coding RNA gene on chromosome 17q21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58254
Approved symbol	LRRC59-AS1
Name	LRRC59 antisense RNA 1
Location	17q21.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253102
Ensembl biotype	lncRNA
Entrez	139355235
RNAcentral	URS0002A18357 — lncRNA, 1872 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000511627, ENST00000802577

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511627 — 2 exons

Exon	Start	End
ENSE00004192276	50397240	50398965
ENSE00004192277	50396358	50396503

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 95.69.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	95.69	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.69	silver quality
skeletal muscle tissue	UBERON:0001134	75.88	silver quality
stromal cell of endometrium	CL:0002255	72.12	gold quality
colonic epithelium	UBERON:0000397	71.22	silver quality
bone marrow cell	CL:0002092	70.84	gold quality
mucosa of transverse colon	UBERON:0004991	67.97	gold quality
ganglionic eminence	UBERON:0004023	66.36	gold quality
ventricular zone	UBERON:0003053	65.31	gold quality
cortical plate	UBERON:0005343	64.74	gold quality
bone marrow	UBERON:0002371	63.79	gold quality
liver	UBERON:0002107	62.41	gold quality
monocyte	CL:0000576	60.49	gold quality
leukocyte	CL:0000738	60.26	gold quality
tonsil	UBERON:0002372	59.34	silver quality
prefrontal cortex	UBERON:0000451	59.22	gold quality
body of pancreas	UBERON:0001150	59.11	gold quality
pancreas	UBERON:0001264	58.94	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.90	gold quality
left adrenal gland	UBERON:0001234	58.47	gold quality
adrenal gland	UBERON:0002369	58.35	gold quality
transverse colon	UBERON:0001157	58.22	gold quality
right adrenal gland	UBERON:0001233	57.71	gold quality
right lobe of liver	UBERON:0001114	57.67	gold quality
placenta	UBERON:0001987	57.45	gold quality
colon	UBERON:0001155	55.99	gold quality
left adrenal gland cortex	UBERON:0035825	55.97	gold quality
blood	UBERON:0000178	55.56	gold quality
kidney	UBERON:0002113	55.48	gold quality
right adrenal gland cortex	UBERON:0035827	55.30	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	14.46
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.