LRRC8D-DT

Summary

LRRC8D-DT (LRRC8D divergent transcript, HGNC:55186) is a long non-coding RNA gene on chromosome 1p22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55186
Approved symbol	LRRC8D-DT
Name	LRRC8D divergent transcript
Location	1p22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272931
Ensembl biotype	lncRNA
Entrez	118568809
RNAcentral	URS00026A2604 — lncRNA, 1621 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000609194

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609194 — 1 exons

Exon	Start	End
ENSE00003704365	89820174	89820868

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 87.26.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.26	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.59	gold quality
adenohypophysis	UBERON:0002196	74.39	gold quality
pituitary gland	UBERON:0000007	70.37	gold quality
monocyte	CL:0000576	70.36	gold quality
leukocyte	CL:0000738	70.36	gold quality
cortical plate	UBERON:0005343	69.85	gold quality
mucosa of transverse colon	UBERON:0004991	69.64	gold quality
granulocyte	CL:0000094	68.52	gold quality
lymph node	UBERON:0000029	67.47	gold quality
adult mammalian kidney	UBERON:0000082	67.44	gold quality
spleen	UBERON:0002106	67.40	gold quality
thyroid gland	UBERON:0002046	67.08	gold quality
metanephros cortex	UBERON:0010533	67.06	gold quality
left lobe of thyroid gland	UBERON:0001120	66.96	gold quality
tonsil	UBERON:0002372	66.70	gold quality
kidney	UBERON:0002113	66.69	gold quality
right lobe of thyroid gland	UBERON:0001119	66.51	gold quality
cerebellar cortex	UBERON:0002129	66.28	gold quality
cerebellar hemisphere	UBERON:0002245	66.28	gold quality
cerebellum	UBERON:0002037	66.25	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.70	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.68	gold quality
bone marrow cell	CL:0002092	65.60	silver quality
bone marrow	UBERON:0002371	65.52	gold quality
cortex of kidney	UBERON:0001225	65.32	gold quality
ganglionic eminence	UBERON:0004023	65.04	gold quality
vermiform appendix	UBERON:0001154	64.59	gold quality
rectum	UBERON:0001052	64.35	gold quality
ventricular zone	UBERON:0003053	64.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.