LRRTM4-AS1

Summary

LRRTM4-AS1 (LRRTM4 antisense RNA 1, HGNC:40889) is a long non-coding RNA gene on chromosome 2p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40889
Approved symbol	LRRTM4-AS1
Name	LRRTM4 antisense RNA 1
Location	2p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234653
Ensembl biotype	lncRNA
Entrez	101927907
RNAcentral	URS000075C12E — lncRNA, 997 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000445178

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445178 — 4 exons

Exon	Start	End
ENSE00001613386	77009024	77009791
ENSE00001729663	76987406	76987494
ENSE00001761403	76989821	76989926
ENSE00001794471	76985965	76986001

Expression profiles

Bgee: expression breadth broad, 26 present calls, max score 81.37.

Top tissues by expression

168 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.37	silver quality
colonic epithelium	UBERON:0000397	60.54	silver quality
corpus callosum	UBERON:0002336	55.77	gold quality
monocyte	CL:0000576	52.60	silver quality
tibial artery	UBERON:0007610	51.71	gold quality
adrenal tissue	UBERON:0018303	51.22	silver quality
prefrontal cortex	UBERON:0000451	46.98	gold quality
islet of Langerhans	UBERON:0000006	46.02	gold quality
aorta	UBERON:0000947	43.83	silver quality
gastrocnemius	UBERON:0001388	43.52	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
Brodmann (1909) area 9	UBERON:0013540	43.05	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
pancreas	UBERON:0001264	42.53	silver quality
thyroid gland	UBERON:0002046	42.15	gold quality
skeletal muscle tissue	UBERON:0001134	42.08	gold quality
blood	UBERON:0000178	42.07	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
frontal cortex	UBERON:0001870	41.48	gold quality
primary visual cortex	UBERON:0002436	41.48	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
neocortex	UBERON:0001950	41.19	gold quality
cardiac ventricle	UBERON:0002082	41.15	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
vagina	UBERON:0000996	40.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.