LUARIS

Summary

LUARIS (lncRNA upregulator of antiviral response interferon signaling, HGNC:40992) is a long non-coding RNA gene on chromosome 7p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40992
Approved symbol	LUARIS
Name	lncRNA upregulator of antiviral response interferon signaling
Location	7p13
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncRNA#32, SCAT6
Ensembl gene	ENSG00000231638
Ensembl biotype	lncRNA
OMIM	618172
Entrez	100506895
RNAcentral	URS000075B2C7 — lncRNA, 2935 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000436105

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436105 — 3 exons

Exon	Start	End
ENSE00001671919	43508728	43510247
ENSE00001691734	43522288	43522542
ENSE00001775786	43510983	43512123

Expression profiles

Bgee: expression breadth broad, 55 present calls, max score 62.70.

Top tissues by expression

175 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	62.70	gold quality
ganglionic eminence	UBERON:0004023	62.46	gold quality
ventricular zone	UBERON:0003053	62.00	gold quality
secondary oocyte	CL:0000655	58.51	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.82	silver quality
calcaneal tendon	UBERON:0003701	50.91	silver quality
apex of heart	UBERON:0002098	50.64	gold quality
oocyte	CL:0000023	48.69	gold quality
gastrocnemius	UBERON:0001388	48.18	gold quality
prefrontal cortex	UBERON:0000451	48.12	silver quality
islet of Langerhans	UBERON:0000006	46.81	silver quality
cerebellar cortex	UBERON:0002129	46.50	gold quality
cerebellar hemisphere	UBERON:0002245	46.36	gold quality
cerebellum	UBERON:0002037	45.71	gold quality
adult mammalian kidney	UBERON:0000082	45.32	gold quality
gall bladder	UBERON:0002110	44.98	gold quality
right hemisphere of cerebellum	UBERON:0014890	44.75	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	44.69	silver quality
cortex of kidney	UBERON:0001225	44.42	silver quality
smooth muscle tissue	UBERON:0001135	44.41	gold quality
upper leg skin	UBERON:0004262	44.20	silver quality
heart left ventricle	UBERON:0002084	44.14	gold quality
heart	UBERON:0000948	43.80	gold quality
pancreas	UBERON:0001264	43.73	silver quality
upper lobe of lung	UBERON:0008948	43.71	silver quality
lower lobe of lung	UBERON:0008949	43.67	silver quality
cardiac ventricle	UBERON:0002082	43.65	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
kidney	UBERON:0002113	43.34	silver quality
skin of hip	UBERON:0001554	43.01	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.