LYPLAL1-AS1

Summary

LYPLAL1-AS1 (LYPLAL1 antisense RNA 1, HGNC:54054) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54054
Approved symbol	LYPLAL1-AS1
Name	LYPLAL1 antisense RNA 1
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228536
Ensembl biotype	lncRNA
Entrez	102723886
RNAcentral	URS0000A77289 — lncRNA, 703 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000420762, ENST00000441790, ENST00000640010, ENST00000652910, ENST00000653604, ENST00000658964, ENST00000664470, ENST00000667916, ENST00000811290, ENST00000811291, ENST00000811292, ENST00000811293, ENST00000811294, ENST00000811295, ENST00000811296, ENST00000811297, ENST00000811298

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420762 — 3 exons

Exon	Start	End
ENSE00001627047	219435152	219435413
ENSE00001659195	219437056	219437173
ENSE00004209078	219442572	219442685

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 85.85.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0107 / max 7.0089, expressed in 5 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
17529	0.0107	5

Top tissues by expression

252 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
body of pancreas	UBERON:0001150	85.85	gold quality
epithelial cell of pancreas	CL:0000083	82.51	gold quality
tibialis anterior	UBERON:0001385	79.52	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.15	gold quality
pancreas	UBERON:0001264	77.43	gold quality
cartilage tissue	UBERON:0002418	76.43	gold quality
pancreatic ductal cell	CL:0002079	74.81	silver quality
subcutaneous adipose tissue	UBERON:0002190	73.56	gold quality
skin of leg	UBERON:0001511	70.03	gold quality
right adrenal gland cortex	UBERON:0035827	69.77	gold quality
colonic epithelium	UBERON:0000397	68.86	silver quality
adipose tissue	UBERON:0001013	68.13	gold quality
kidney epithelium	UBERON:0004819	68.11	gold quality
skin of abdomen	UBERON:0001416	67.71	gold quality
deltoid	UBERON:0001476	67.20	gold quality
zone of skin	UBERON:0000014	67.06	gold quality
adult mammalian kidney	UBERON:0000082	67.02	gold quality
left ovary	UBERON:0002119	66.96	gold quality
omental fat pad	UBERON:0010414	66.60	gold quality
peritoneum	UBERON:0002358	66.57	gold quality
right adrenal gland	UBERON:0001233	66.39	gold quality
ileal mucosa	UBERON:0000331	66.34	silver quality
left ventricle myocardium	UBERON:0006566	66.19	gold quality
smooth muscle tissue	UBERON:0001135	66.05	gold quality
right ovary	UBERON:0002118	66.05	gold quality
cardiac muscle of right atrium	UBERON:0003379	65.99	gold quality
adipose tissue of abdominal region	UBERON:0007808	65.88	gold quality
ectocervix	UBERON:0012249	65.64	gold quality
islet of Langerhans	UBERON:0000006	64.69	gold quality
adrenal cortex	UBERON:0001235	64.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.