LYPLAL1-DT

Summary

LYPLAL1-DT (LYPLAL1 divergent transcript, HGNC:50560) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50560
Approved symbol	LYPLAL1-DT
Name	LYPLAL1 divergent transcript
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228063
Ensembl biotype	lncRNA
Entrez	643723
RNAcentral	URS000075B5F8 — lncRNA, 1642 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 97 — 97 lncRNA

ENST00000441331, ENST00000654859, ENST00000655283, ENST00000657470, ENST00000658274, ENST00000661230, ENST00000663684, ENST00000668290, ENST00000669535, ENST00000670257, ENST00000670576, ENST00000685043, ENST00000685426, ENST00000685878, ENST00000686513, ENST00000687117, ENST00000690528, ENST00000691001, ENST00000692527, ENST00000702786, ENST00000702804, ENST00000811048, ENST00000811049, ENST00000811050, ENST00000811051, ENST00000811052, ENST00000811053, ENST00000811054, ENST00000811055, ENST00000811056, ENST00000811057, ENST00000811058, ENST00000811059, ENST00000811060, ENST00000811061, ENST00000811062, ENST00000811063, ENST00000811064, ENST00000811065, ENST00000811066, ENST00000811067, ENST00000811068, ENST00000811069, ENST00000811070, ENST00000811071, ENST00000811072, ENST00000811073, ENST00000811074, ENST00000811075, ENST00000811076, ENST00000811077, ENST00000811078, ENST00000811079, ENST00000811080, ENST00000811081, ENST00000811082, ENST00000811083, ENST00000811084, ENST00000811085, ENST00000811086, ENST00000811087, ENST00000811088, ENST00000811089, ENST00000811090, ENST00000811091, ENST00000811092, ENST00000811093, ENST00000811094, ENST00000811095, ENST00000811096, ENST00000811097, ENST00000811098, ENST00000811099, ENST00000811100, ENST00000811101, ENST00000811102, ENST00000811103, ENST00000811104, ENST00000811105, ENST00000811106, ENST00000811107, ENST00000811108, ENST00000811109, ENST00000811110, ENST00000811111, ENST00000811112, ENST00000811113, ENST00000811114, ENST00000811115, ENST00000811116, ENST00000811117, ENST00000811118, ENST00000811119, ENST00000811120, ENST00000811121, ENST00000811122, ENST00000811123

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441331 — 4 exons

Exon	Start	End
ENSE00001709578	219156120	219156199
ENSE00001796922	219149939	219150031
ENSE00004208646	219100616	219100754
ENSE00004208700	219173470	219173799

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 85.31.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8318 / max 97.8265, expressed in 323 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
17516	0.4859	212
17525	0.1588	46
17524	0.0831	32
17521	0.0289	3
17527	0.0254	9
17522	0.0195	2
17526	0.0194	10
17523	0.0107	1

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	85.31	gold quality
leukocyte	CL:0000738	83.90	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.86	gold quality
sural nerve	UBERON:0015488	78.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.64	gold quality
popliteal artery	UBERON:0002250	68.77	gold quality
tibial artery	UBERON:0007610	68.72	gold quality
bone marrow cell	CL:0002092	68.61	silver quality
skeletal muscle tissue	UBERON:0001134	68.19	gold quality
muscle tissue	UBERON:0002385	67.99	gold quality
right coronary artery	UBERON:0001625	67.80	gold quality
smooth muscle tissue	UBERON:0001135	67.70	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.53	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.06	gold quality
corpus callosum	UBERON:0002336	66.12	gold quality
colonic epithelium	UBERON:0000397	66.09	silver quality
substantia nigra	UBERON:0002038	65.63	gold quality
ventricular zone	UBERON:0003053	65.36	gold quality
left coronary artery	UBERON:0001626	65.33	gold quality
tonsil	UBERON:0002372	65.29	gold quality
prefrontal cortex	UBERON:0000451	65.15	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.91	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.52	gold quality
lower esophagus	UBERON:0013473	64.49	gold quality
body of uterus	UBERON:0009853	64.25	gold quality
thoracic aorta	UBERON:0001515	64.23	gold quality
heart left ventricle	UBERON:0002084	64.23	gold quality
ascending aorta	UBERON:0001496	64.03	gold quality
putamen	UBERON:0001874	63.67	gold quality
islet of Langerhans	UBERON:0000006	63.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.