LYRM4-AS1

Summary

LYRM4-AS1 (LYRM4 antisense RNA 1, HGNC:52055) is a long non-coding RNA gene on chromosome 6p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52055
Approved symbol	LYRM4-AS1
Name	LYRM4 antisense RNA 1
Location	6p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272142
Ensembl biotype	lncRNA
Entrez	100129461
RNAcentral	URS00007E40C3 — lncRNA, 3162 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000606761, ENST00000606767, ENST00000607327, ENST00000653195, ENST00000654379, ENST00000654506, ENST00000655306, ENST00000655665, ENST00000657816, ENST00000657867, ENST00000659006, ENST00000661051, ENST00000661080, ENST00000661740, ENST00000663198, ENST00000665374, ENST00000666518, ENST00000666739, ENST00000671039, ENST00000766823, ENST00000766824, ENST00000766825, ENST00000766826

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606761 — 2 exons

Exon	Start	End
ENSE00003695925	5029972	5030195
ENSE00003696862	5042588	5043449

Expression profiles

Bgee: expression breadth ubiquitous, 164 present calls, max score 81.27.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 6.0091 / max 51.7097, expressed in 1648 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
65584	5.9935	1648
65585	0.0157	4

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.27	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.39	gold quality
stromal cell of endometrium	CL:0002255	76.90	gold quality
left testis	UBERON:0004533	76.42	gold quality
left adrenal gland	UBERON:0001234	75.48	gold quality
adrenal tissue	UBERON:0018303	75.48	gold quality
right adrenal gland cortex	UBERON:0035827	75.46	gold quality
right adrenal gland	UBERON:0001233	75.26	gold quality
testis	UBERON:0000473	75.08	gold quality
left adrenal gland cortex	UBERON:0035825	75.07	gold quality
right testis	UBERON:0004534	75.04	gold quality
islet of Langerhans	UBERON:0000006	74.47	gold quality
adrenal gland	UBERON:0002369	74.40	gold quality
smooth muscle tissue	UBERON:0001135	74.28	gold quality
adrenal cortex	UBERON:0001235	72.73	gold quality
popliteal artery	UBERON:0002250	70.12	gold quality
tibial artery	UBERON:0007610	70.07	gold quality
ventricular zone	UBERON:0003053	69.96	gold quality
lower esophagus	UBERON:0013473	69.67	gold quality
lower esophagus muscularis layer	UBERON:0035833	69.64	gold quality
muscle layer of sigmoid colon	UBERON:0035805	69.52	gold quality
vermiform appendix	UBERON:0001154	69.12	gold quality
esophagus	UBERON:0001043	69.06	gold quality
left coronary artery	UBERON:0001626	69.00	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.70	gold quality
esophagus mucosa	UBERON:0002469	68.59	gold quality
body of uterus	UBERON:0009853	68.31	gold quality
bone marrow cell	CL:0002092	68.17	silver quality
aorta	UBERON:0000947	67.98	gold quality
sperm	CL:0000019	67.95	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.03

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.