LZTS1-AS1

Summary

LZTS1-AS1 (LZTS1 antisense RNA 1, HGNC:43630) is a long non-coding RNA gene on chromosome 8p21.3.

Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome.

Source: NCBI Gene 100874051 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43630
Approved symbol	LZTS1-AS1
Name	LZTS1 antisense RNA 1
Location	8p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253733
Ensembl biotype	lncRNA
Entrez	100874051
RNAcentral	URS000048471C — lncRNA, 892 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000523103

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000523103 — 3 exons

Exon	Start	End
ENSE00002103103	20289809	20290458
ENSE00002116374	20289209	20289308
ENSE00002133391	20275773	20275914

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 99.61.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	99.61	gold quality
sural nerve	UBERON:0015488	62.34	gold quality
primary visual cortex	UBERON:0002436	55.77	gold quality
endometrium	UBERON:0001295	54.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	54.42	gold quality
left testis	UBERON:0004533	53.78	gold quality
right testis	UBERON:0004534	53.72	gold quality
testis	UBERON:0000473	53.48	gold quality
blood	UBERON:0000178	51.63	gold quality
islet of Langerhans	UBERON:0000006	50.50	gold quality
lung	UBERON:0002048	50.43	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.17	gold quality
calcaneal tendon	UBERON:0003701	49.03	silver quality
myometrium	UBERON:0001296	48.10	gold quality
multicellular organism	UBERON:0000468	47.65	gold quality
heart	UBERON:0000948	47.31	gold quality
monocyte	CL:0000576	47.27	silver quality
placenta	UBERON:0001987	47.12	silver quality
prefrontal cortex	UBERON:0000451	47.02	silver quality
heart left ventricle	UBERON:0002084	46.98	gold quality
left coronary artery	UBERON:0001626	46.56	gold quality
adrenal gland	UBERON:0002369	45.23	silver quality
gastrocnemius	UBERON:0001388	44.93	gold quality
tibial artery	UBERON:0007610	44.79	silver quality
stomach	UBERON:0000945	44.48	silver quality
intestine	UBERON:0000160	44.42	silver quality
superior frontal gyrus	UBERON:0002661	44.39	silver quality
body of stomach	UBERON:0001161	43.90	silver quality
esophagus	UBERON:0001043	43.88	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.