MACROD2-AS1

Summary

MACROD2-AS1 (MACROD2 antisense RNA 1, HGNC:37193) is a long non-coding RNA gene on chromosome 20p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37193
Approved symbol	MACROD2-AS1
Name	MACROD2 antisense RNA 1
Location	20p12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	BA318C17.1
Ensembl gene	ENSG00000235914
Ensembl biotype	lncRNA
Entrez	100379174
RNAcentral	URS000075C9CB — lncRNA, 695 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000439451, ENST00000455291, ENST00000653740, ENST00000664409, ENST00000738173, ENST00000738174, ENST00000738175

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439451 — 2 exons

Exon	Start	End
ENSE00001606252	14904941	14906029
ENSE00001765202	14929375	14929515

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 91.76.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0218 / max 18.4945, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
186480	0.0218	3

Top tissues by expression

206 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	91.76	gold quality
sperm	CL:0000019	90.83	gold quality
right testis	UBERON:0004534	90.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.95	gold quality
testis	UBERON:0000473	87.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.69	gold quality
sural nerve	UBERON:0015488	65.76	silver quality
colonic epithelium	UBERON:0000397	60.91	silver quality
ganglionic eminence	UBERON:0004023	60.11	gold quality
ventricular zone	UBERON:0003053	60.03	gold quality
adrenal tissue	UBERON:0018303	58.93	gold quality
corpus callosum	UBERON:0002336	56.53	gold quality
monocyte	CL:0000576	55.60	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.36	silver quality
uterine cervix	UBERON:0000002	52.81	silver quality
calcaneal tendon	UBERON:0003701	52.03	gold quality
muscle of leg	UBERON:0001383	50.96	gold quality
upper leg skin	UBERON:0004262	50.92	silver quality
stomach	UBERON:0000945	50.84	gold quality
gastrocnemius	UBERON:0001388	49.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.46	gold quality
islet of Langerhans	UBERON:0000006	49.37	gold quality
prefrontal cortex	UBERON:0000451	48.66	gold quality
liver	UBERON:0002107	48.15	silver quality
tonsil	UBERON:0002372	48.04	silver quality
adrenal gland	UBERON:0002369	46.88	gold quality
anatomical system	UBERON:0000467	46.58	gold quality
right lobe of liver	UBERON:0001114	46.50	silver quality
material anatomical entity	UBERON:0000465	46.40	gold quality
tendon	UBERON:0000043	46.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.