MACROD2-IT1

Summary

MACROD2-IT1 (MACROD2 intronic transcript 1, HGNC:16201) is a long non-coding RNA gene on chromosome 20p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16201
Approved symbol	MACROD2-IT1
Name	MACROD2 intronic transcript 1
Location	20p12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA467D7.4
Ensembl gene	ENSG00000227927
Ensembl biotype	lncRNA
Entrez	140848
RNAcentral	URS0000364A4B — lncRNA, 665 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000448536, ENST00000605675

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000448536 — 5 exons

Exon	Start	End
ENSE00001629536	14627064	14627106
ENSE00001638587	14554384	14554428
ENSE00001679108	14628637	14628908
ENSE00001703131	14621766	14621929
ENSE00001794938	14622874	14623014

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 88.18.

Top tissues by expression

83 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.18	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.53	gold quality
urinary bladder	UBERON:0001255	61.16	silver quality
skeletal muscle tissue	UBERON:0001134	61.10	silver quality
monocyte	CL:0000576	59.25	gold quality
islet of Langerhans	UBERON:0000006	57.90	gold quality
corpus callosum	UBERON:0002336	57.21	gold quality
blood	UBERON:0000178	53.93	gold quality
endometrium	UBERON:0001295	52.55	silver quality
liver	UBERON:0002107	51.89	silver quality
Brodmann (1909) area 9	UBERON:0013540	51.85	gold quality
calcaneal tendon	UBERON:0003701	50.64	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	50.60	gold quality
superior frontal gyrus	UBERON:0002661	50.50	gold quality
right lobe of liver	UBERON:0001114	50.49	silver quality
right lobe of thyroid gland	UBERON:0001119	49.35	gold quality
myometrium	UBERON:0001296	48.73	silver quality
prefrontal cortex	UBERON:0000451	48.38	gold quality
thoracic mammary gland	UBERON:0005200	48.24	silver quality
adrenal tissue	UBERON:0018303	47.67	silver quality
heart	UBERON:0000948	47.27	silver quality
tibial artery	UBERON:0007610	47.05	gold quality
right testis	UBERON:0004534	46.66	gold quality
gastrocnemius	UBERON:0001388	46.60	silver quality
testis	UBERON:0000473	46.57	gold quality
left testis	UBERON:0004533	46.55	gold quality
cerebellum	UBERON:0002037	46.16	silver quality
adrenal gland	UBERON:0002369	45.84	gold quality
kidney	UBERON:0002113	45.80	gold quality
adult mammalian kidney	UBERON:0000082	45.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.