MADD-AS1

Summary

MADD-AS1 (MADD antisense RNA 1, HGNC:40354) is a long non-coding RNA gene on chromosome 11p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40354
Approved symbol	MADD-AS1
Name	MADD antisense RNA 1
Location	11p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256746
Ensembl biotype	lncRNA
Entrez	101928943
RNAcentral	URS000075EBB3 — lncRNA, 501 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000543925, ENST00000545474

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000543925 — 3 exons

Exon	Start	End
ENSE00002215597	47271079	47271141
ENSE00002266827	47270657	47270980
ENSE00002295005	47272076	47272110

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 96.06.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.06	gold quality
adrenal tissue	UBERON:0018303	71.27	gold quality
stromal cell of endometrium	CL:0002255	69.74	gold quality
ventricular zone	UBERON:0003053	69.11	gold quality
colonic epithelium	UBERON:0000397	68.81	gold quality
bone marrow cell	CL:0002092	68.60	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.93	gold quality
granulocyte	CL:0000094	66.78	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.45	gold quality
ganglionic eminence	UBERON:0004023	66.33	gold quality
cerebellar hemisphere	UBERON:0002245	66.23	gold quality
cerebellar cortex	UBERON:0002129	66.00	gold quality
cerebellum	UBERON:0002037	64.23	gold quality
sural nerve	UBERON:0015488	63.02	silver quality
monocyte	CL:0000576	62.86	gold quality
right coronary artery	UBERON:0001625	62.73	gold quality
calcaneal tendon	UBERON:0003701	62.05	gold quality
right lung	UBERON:0002167	60.88	gold quality
corpus callosum	UBERON:0002336	60.55	gold quality
vermiform appendix	UBERON:0001154	58.81	gold quality
lymph node	UBERON:0000029	58.71	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.47	gold quality
islet of Langerhans	UBERON:0000006	58.37	gold quality
prefrontal cortex	UBERON:0000451	58.20	gold quality
muscle of leg	UBERON:0001383	57.51	gold quality
gall bladder	UBERON:0002110	57.14	gold quality
right atrium auricular region	UBERON:0006631	56.79	gold quality
gastrocnemius	UBERON:0001388	56.62	gold quality
popliteal artery	UBERON:0002250	56.62	gold quality
tibial artery	UBERON:0007610	56.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.