MAFA-AS1

Summary

MAFA-AS1 (MAFA antisense RNA 1, HGNC:51203) is a long non-coding RNA gene on chromosome 8q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51203
Approved symbol	MAFA-AS1
Name	MAFA antisense RNA 1
Location	8q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-909N17.2, RP11-909N17.3, TCONS_00014882
Ensembl gene	ENSG00000254338
Ensembl biotype	lncRNA
Entrez	104326051
RNAcentral	URS00026A2457 — lncRNA, 1485 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000519762, ENST00000523002, ENST00000790480, ENST00000790481, ENST00000790482, ENST00000790483, ENST00000850926

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000519762 — 2 exons

Exon	Start	End
ENSE00002095491	143417679	143417919
ENSE00002112352	143418975	143419150

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 89.43.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.43	gold quality
gastrocnemius	UBERON:0001388	77.07	gold quality
muscle of leg	UBERON:0001383	76.89	gold quality
sural nerve	UBERON:0015488	75.97	gold quality
skeletal muscle tissue	UBERON:0001134	75.50	gold quality
ganglionic eminence	UBERON:0004023	73.00	gold quality
cortical plate	UBERON:0005343	72.96	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.30	gold quality
lower esophagus mucosa	UBERON:0035834	72.03	gold quality
muscle tissue	UBERON:0002385	71.59	gold quality
islet of Langerhans	UBERON:0000006	71.25	gold quality
blood	UBERON:0000178	71.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.01	gold quality
ventricular zone	UBERON:0003053	68.83	gold quality
vagina	UBERON:0000996	68.34	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.22	gold quality
apex of heart	UBERON:0002098	66.97	gold quality
mucosa of stomach	UBERON:0001199	63.23	gold quality
lymph node	UBERON:0000029	62.67	gold quality
uterine cervix	UBERON:0000002	62.01	gold quality
ectocervix	UBERON:0012249	61.90	gold quality
bone marrow	UBERON:0002371	61.60	gold quality
cortex of kidney	UBERON:0001225	61.22	gold quality
right lung	UBERON:0002167	60.60	gold quality
spleen	UBERON:0002106	59.93	gold quality
placenta	UBERON:0001987	59.84	gold quality
adenohypophysis	UBERON:0002196	58.68	gold quality
endocervix	UBERON:0000458	58.43	gold quality
kidney	UBERON:0002113	58.05	gold quality
stromal cell of endometrium	CL:0002255	57.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.