MAGEA4-AS1

Summary

MAGEA4-AS1 (MAGEA4 antisense RNA 1, HGNC:53860) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53860
Approved symbol	MAGEA4-AS1
Name	MAGEA4 antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229967
Ensembl biotype	lncRNA
Entrez	105373368
RNAcentral	URS0000A764E0 — lncRNA, 432 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 36 — 36 lncRNA

ENST00000411474, ENST00000424126, ENST00000445330, ENST00000835372, ENST00000835373, ENST00000835374, ENST00000835375, ENST00000835376, ENST00000835377, ENST00000835378, ENST00000835379, ENST00000835380, ENST00000835381, ENST00000835382, ENST00000835383, ENST00000835384, ENST00000835385, ENST00000835386, ENST00000835387, ENST00000835388, ENST00000835389, ENST00000835390, ENST00000835391, ENST00000835392, ENST00000835393, ENST00000835394, ENST00000835395, ENST00000835396, ENST00000835397, ENST00000835398, ENST00000835399, ENST00000835400, ENST00000835401, ENST00000835402, ENST00000835403, ENST00000835404

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411474 — 3 exons

Exon	Start	End
ENSE00001691684	151907342	151907399
ENSE00004253830	151911023	151912400
ENSE00004253833	151904431	151904789

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 86.00.

Top tissues by expression

47 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.00	gold quality
pituitary gland	UBERON:0000007	76.80	gold quality
sural nerve	UBERON:0015488	72.58	silver quality
muscle layer of sigmoid colon	UBERON:0035805	70.58	gold quality
right testis	UBERON:0004534	65.54	gold quality
left testis	UBERON:0004533	65.53	gold quality
testis	UBERON:0000473	65.12	gold quality
placenta	UBERON:0001987	64.84	gold quality
multicellular organism	UBERON:0000468	59.60	gold quality
tibial nerve	UBERON:0001323	58.67	gold quality
putamen	UBERON:0001874	55.54	gold quality
substantia nigra	UBERON:0002038	53.88	gold quality
prefrontal cortex	UBERON:0000451	52.91	gold quality
blood	UBERON:0000178	52.49	gold quality
lymph node	UBERON:0000029	52.14	gold quality
amygdala	UBERON:0001876	52.09	gold quality
anterior cingulate cortex	UBERON:0009835	51.79	gold quality
gastrocnemius	UBERON:0001388	50.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	49.33	gold quality
Ammon’s horn	UBERON:0001954	48.57	gold quality
monocyte	CL:0000576	48.50	silver quality
cerebral cortex	UBERON:0000956	48.13	gold quality
right frontal lobe	UBERON:0002810	47.47	gold quality
body of pancreas	UBERON:0001150	47.31	silver quality
lower esophagus muscularis layer	UBERON:0035833	47.03	gold quality
adipose tissue	UBERON:0001013	45.47	gold quality
caudate nucleus	UBERON:0001873	44.28	gold quality
nucleus accumbens	UBERON:0001882	43.60	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.41	gold quality
heart left ventricle	UBERON:0002084	42.81	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.