MAGEA8-AS1

Summary

MAGEA8-AS1 (MAGEA8 antisense RNA 1, HGNC:45093) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45093
Approved symbol	MAGEA8-AS1
Name	MAGEA8 antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP5-869M20.2
Ensembl gene	ENSG00000230899
Ensembl biotype	lncRNA
Entrez	101410537
RNAcentral	URS000075E63C — lncRNA, 596 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000427671, ENST00000807375, ENST00000807376, ENST00000807377

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427671 — 5 exons

Exon	Start	End
ENSE00001690540	149880096	149880192
ENSE00001737620	149879801	149879858
ENSE00001753315	149879266	149879358
ENSE00004201374	149878441	149878996
ENSE00004201380	149881004	149881155

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 74.18.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.18	gold quality
placenta	UBERON:0001987	62.67	gold quality
lymph node	UBERON:0000029	61.94	gold quality
sural nerve	UBERON:0015488	60.96	silver quality
monocyte	CL:0000576	59.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.01	gold quality
right coronary artery	UBERON:0001625	56.80	gold quality
cerebellar cortex	UBERON:0002129	55.78	gold quality
cerebellum	UBERON:0002037	55.77	gold quality
islet of Langerhans	UBERON:0000006	55.69	gold quality
cerebellar hemisphere	UBERON:0002245	55.67	gold quality
vermiform appendix	UBERON:0001154	55.59	gold quality
bone marrow	UBERON:0002371	55.15	gold quality
gall bladder	UBERON:0002110	55.06	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.83	gold quality
primary visual cortex	UBERON:0002436	53.85	gold quality
prefrontal cortex	UBERON:0000451	53.74	gold quality
ectocervix	UBERON:0012249	52.65	gold quality
superior frontal gyrus	UBERON:0002661	52.59	gold quality
muscle of leg	UBERON:0001383	52.48	gold quality
liver	UBERON:0002107	52.24	silver quality
right ovary	UBERON:0002118	52.09	gold quality
mucosa of stomach	UBERON:0001199	52.03	gold quality
urinary bladder	UBERON:0001255	52.01	gold quality
gastrocnemius	UBERON:0001388	51.74	gold quality
popliteal artery	UBERON:0002250	51.70	gold quality
tibial artery	UBERON:0007610	51.64	gold quality
myometrium	UBERON:0001296	51.59	gold quality
right lobe of liver	UBERON:0001114	51.58	silver quality
cortex of kidney	UBERON:0001225	50.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.