MAGEB17-AS1

Summary

MAGEB17-AS1 (MAGEB17 antisense RNA 1, HGNC:56739) is a long non-coding RNA gene on chromosome Xp22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56739
Approved symbol	MAGEB17-AS1
Name	MAGEB17 antisense RNA 1
Location	Xp22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-AP1S2-2
Ensembl gene	ENSG00000238178
Ensembl biotype	lncRNA
Entrez	128966703
RNAcentral	URS00026A217C — lncRNA, 2070 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000422438, ENST00000435789, ENST00000454712, ENST00000809341, ENST00000809342, ENST00000809343

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422438 — 4 exons

Exon	Start	End
ENSE00001618679	16152941	16153102
ENSE00001641044	16153394	16153463
ENSE00001751813	16154598	16154680
ENSE00001794142	16157753	16157829

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 90.83.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.83	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.57	gold quality
body of pancreas	UBERON:0001150	79.69	gold quality
pancreas	UBERON:0001264	74.00	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	72.63	gold quality
lower esophagus muscularis layer	UBERON:0035833	70.15	gold quality
lower esophagus	UBERON:0013473	70.09	gold quality
stromal cell of endometrium	CL:0002255	69.55	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.53	gold quality
skeletal muscle tissue	UBERON:0001134	64.38	gold quality
esophagus	UBERON:0001043	64.04	gold quality
smooth muscle tissue	UBERON:0001135	63.26	gold quality
mucosa of stomach	UBERON:0001199	63.06	gold quality
cortical plate	UBERON:0005343	62.36	gold quality
body of stomach	UBERON:0001161	61.73	gold quality
leukocyte	CL:0000738	61.52	gold quality
fundus of stomach	UBERON:0001160	61.14	gold quality
monocyte	CL:0000576	61.04	gold quality
stomach	UBERON:0000945	60.93	gold quality
gall bladder	UBERON:0002110	60.60	gold quality
mucosa of transverse colon	UBERON:0004991	60.26	gold quality
duodenum	UBERON:0002114	59.65	gold quality
ganglionic eminence	UBERON:0004023	59.38	gold quality
transverse colon	UBERON:0001157	58.87	gold quality
prefrontal cortex	UBERON:0000451	58.81	gold quality
muscle layer of sigmoid colon	UBERON:0035805	58.80	gold quality
colon	UBERON:0001155	58.47	gold quality
sural nerve	UBERON:0015488	58.15	silver quality
rectum	UBERON:0001052	58.06	gold quality
endometrium	UBERON:0001295	57.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.