MAGI2-AS1

Summary

MAGI2-AS1 (MAGI2 antisense RNA 1, HGNC:40860) is a long non-coding RNA gene on chromosome 7q21.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40860
Approved symbol	MAGI2-AS1
Name	MAGI2 antisense RNA 1
Location	7q21.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251276
Ensembl biotype	lncRNA
Entrez	100874020
RNAcentral	URS000058D833 — lncRNA, 472 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000428298

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428298 — 2 exons

Exon	Start	End
ENSE00001633419	78939850	78939884
ENSE00001721509	78940459	78940895

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 88.56.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	88.56	gold quality
colonic epithelium	UBERON:0000397	80.57	gold quality
adrenal tissue	UBERON:0018303	65.85	gold quality
calcaneal tendon	UBERON:0003701	64.00	gold quality
temporal lobe	UBERON:0001871	63.41	gold quality
kidney	UBERON:0002113	61.44	gold quality
urinary bladder	UBERON:0001255	59.28	silver quality
prefrontal cortex	UBERON:0000451	58.57	gold quality
liver	UBERON:0002107	57.54	gold quality
superior frontal gyrus	UBERON:0002661	54.70	gold quality
cortex of kidney	UBERON:0001225	53.26	gold quality
endometrium	UBERON:0001295	52.51	gold quality
endocervix	UBERON:0000458	52.22	gold quality
monocyte	CL:0000576	52.14	gold quality
primary visual cortex	UBERON:0002436	50.66	gold quality
islet of Langerhans	UBERON:0000006	50.42	gold quality
blood	UBERON:0000178	50.08	silver quality
left coronary artery	UBERON:0001626	49.31	gold quality
adult mammalian kidney	UBERON:0000082	49.30	gold quality
heart	UBERON:0000948	49.19	gold quality
adrenal gland	UBERON:0002369	49.18	gold quality
lung	UBERON:0002048	48.54	gold quality
myometrium	UBERON:0001296	48.48	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.89	gold quality
body of pancreas	UBERON:0001150	47.26	gold quality
heart left ventricle	UBERON:0002084	46.84	gold quality
adenohypophysis	UBERON:0002196	46.80	gold quality
stomach	UBERON:0000945	46.46	gold quality
cerebellar cortex	UBERON:0002129	46.36	silver quality
gastrocnemius	UBERON:0001388	46.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• this study identified a novel mechanism that MAGI2-AS3/miR-15b-5p/CCDC19 signaling pathway regulates bladder cancer progression. (PMID:30442369)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.