MAGI2-AS2

Summary

MAGI2-AS2 (MAGI2 antisense RNA 2, HGNC:40861) is a long non-coding RNA gene on chromosome 7q21.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40861
Approved symbol	MAGI2-AS2
Name	MAGI2 antisense RNA 2
Location	7q21.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226978
Ensembl biotype	lncRNA
Entrez	100874021
RNAcentral	URS00003B4D20 — lncRNA, 476 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000411616

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411616 — 3 exons

Exon	Start	End
ENSE00001632484	79010927	79011071
ENSE00001647442	79012084	79012277
ENSE00001804291	79008988	79009124

Expression profiles

Bgee: expression breadth broad, 88 present calls, max score 84.70.

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.70	silver quality
left testis	UBERON:0004533	57.07	gold quality
monocyte	CL:0000576	55.83	gold quality
testis	UBERON:0000473	55.39	gold quality
sperm	CL:0000019	55.35	silver quality
right testis	UBERON:0004534	54.18	gold quality
calcaneal tendon	UBERON:0003701	53.05	silver quality
corpus callosum	UBERON:0002336	52.07	gold quality
endocervix	UBERON:0000458	50.52	gold quality
prefrontal cortex	UBERON:0000451	50.33	gold quality
gastrocnemius	UBERON:0001388	49.61	gold quality
cerebellar cortex	UBERON:0002129	48.16	gold quality
tibial artery	UBERON:0007610	47.95	gold quality
cerebellar hemisphere	UBERON:0002245	47.94	gold quality
anterior cingulate cortex	UBERON:0009835	47.73	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.45	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.23	gold quality
amygdala	UBERON:0001876	47.21	gold quality
adrenal tissue	UBERON:0018303	47.14	silver quality
right atrium auricular region	UBERON:0006631	46.39	gold quality
cerebellum	UBERON:0002037	46.24	gold quality
hypothalamus	UBERON:0001898	46.05	gold quality
adult mammalian kidney	UBERON:0000082	45.95	gold quality
heart left ventricle	UBERON:0002084	45.50	gold quality
uterine cervix	UBERON:0000002	45.49	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.49	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	45.33	gold quality
substantia nigra	UBERON:0002038	45.28	gold quality
left coronary artery	UBERON:0001626	45.23	gold quality
aorta	UBERON:0000947	45.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.