MALRD1-AS1

Summary

MALRD1-AS1 (MALRD1 antisense RNA 1, HGNC:58180) is a long non-coding RNA gene on chromosome 10p12.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58180
Approved symbol	MALRD1-AS1
Name	MALRD1 antisense RNA 1
Location	10p12.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233968
Ensembl biotype	lncRNA
Entrez	101928834
RNAcentral	URS000075DDEC — lncRNA, 1397 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000423551, ENST00000431157, ENST00000451713, ENST00000657622, ENST00000688210, ENST00000693194, ENST00000702080, ENST00000702231, ENST00000702247, ENST00000702288, ENST00000702382, ENST00000702501, ENST00000819487, ENST00000819488, ENST00000819489, ENST00000819490, ENST00000819491, ENST00000819492, ENST00000819493, ENST00000819494, ENST00000819495, ENST00000819496

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423551 — 4 exons

Exon	Start	End
ENSE00001642034	19728405	19728550
ENSE00001692639	19721978	19722225
ENSE00001702042	19722330	19722588
ENSE00001743894	19724927	19724981

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 84.16.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	84.16	gold quality
leukocyte	CL:0000738	82.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.92	gold quality
buccal mucosa cell	CL:0002336	77.32	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.98	gold quality
gall bladder	UBERON:0002110	70.45	gold quality
bone marrow cell	CL:0002092	67.35	silver quality
granulocyte	CL:0000094	65.58	gold quality
rectum	UBERON:0001052	63.49	gold quality
smooth muscle tissue	UBERON:0001135	63.31	gold quality
ganglionic eminence	UBERON:0004023	63.21	gold quality
right lung	UBERON:0002167	62.92	gold quality
cortical plate	UBERON:0005343	62.90	gold quality
calcaneal tendon	UBERON:0003701	62.80	gold quality
upper lobe of left lung	UBERON:0008952	62.22	gold quality
colonic epithelium	UBERON:0000397	62.03	silver quality
upper lobe of lung	UBERON:0008948	61.90	gold quality
small intestine Peyer’s patch	UBERON:0003454	61.45	gold quality
mucosa of transverse colon	UBERON:0004991	61.02	gold quality
mucosa of stomach	UBERON:0001199	60.93	gold quality
right uterine tube	UBERON:0001302	60.34	gold quality
small intestine	UBERON:0002108	60.11	gold quality
right coronary artery	UBERON:0001625	59.91	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	59.49	gold quality
lower esophagus muscularis layer	UBERON:0035833	58.63	gold quality
lower esophagus	UBERON:0013473	58.60	gold quality
lung	UBERON:0002048	58.01	gold quality
tibial nerve	UBERON:0001323	57.56	gold quality
lower lobe of lung	UBERON:0008949	57.22	silver quality
skin of leg	UBERON:0001511	56.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LOC101928834, a novel lncRNA in Wnt/beta-catenin signaling pathway, promotes cell proliferation and predicts poor clinical outcome in myelodysplastic syndromes. (PMID:32463458)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.