MALT1-AS1

Summary

MALT1-AS1 (MALT1 antisense RNA 1, HGNC:55306) is a long non-coding RNA gene on chromosome 18q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55306
Approved symbol	MALT1-AS1
Name	MALT1 antisense RNA 1
Location	18q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267226
Ensembl biotype	lncRNA
Entrez	101927322
RNAcentral	URS0000EEACD1 — lncRNA, 1205 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000588144, ENST00000769966, ENST00000769967, ENST00000769968, ENST00000769969

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000588144 — 2 exons

Exon	Start	End
ENSE00002739018	58670009	58670808
ENSE00002865045	58671469	58671877

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 93.15.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	93.15	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.80	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.77	gold quality
sural nerve	UBERON:0015488	84.62	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
ventricular zone	UBERON:0003053	66.13	gold quality
skeletal muscle tissue	UBERON:0001134	65.06	gold quality
bone marrow cell	CL:0002092	64.36	silver quality
hindlimb stylopod muscle	UBERON:0004252	61.67	gold quality
granulocyte	CL:0000094	61.33	gold quality
ganglionic eminence	UBERON:0004023	60.56	gold quality
testis	UBERON:0000473	60.20	gold quality
left testis	UBERON:0004533	60.03	gold quality
tonsil	UBERON:0002372	60.01	gold quality
muscle of leg	UBERON:0001383	59.29	gold quality
gastrocnemius	UBERON:0001388	58.91	gold quality
right testis	UBERON:0004534	58.31	gold quality
bone marrow	UBERON:0002371	57.76	gold quality
monocyte	CL:0000576	56.96	gold quality
stromal cell of endometrium	CL:0002255	56.94	gold quality
lymph node	UBERON:0000029	56.39	gold quality
cortical plate	UBERON:0005343	55.52	silver quality
prefrontal cortex	UBERON:0000451	55.23	gold quality
kidney	UBERON:0002113	55.21	gold quality
liver	UBERON:0002107	54.87	gold quality
adult mammalian kidney	UBERON:0000082	54.86	gold quality
mucosa of transverse colon	UBERON:0004991	54.68	gold quality
superior frontal gyrus	UBERON:0002661	54.65	gold quality
primary visual cortex	UBERON:0002436	54.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.