MAML3-AS1

Summary

MAML3-AS1 (MAML3 antisense RNA 1, HGNC:58423) is a long non-coding RNA gene on chromosome 4q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58423
Approved symbol	MAML3-AS1
Name	MAML3 antisense RNA 1
Location	4q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250698
Ensembl biotype	lncRNA
Entrez	101927516

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000509184, ENST00000774836, ENST00000774837, ENST00000774838, ENST00000774839

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509184 — 3 exons

Exon	Start	End
ENSE00002021653	140133051	140133117
ENSE00002064677	140128015	140128087
ENSE00002076445	140134049	140134565

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 83.44.

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.44	gold quality
adrenal tissue	UBERON:0018303	78.31	gold quality
colonic epithelium	UBERON:0000397	75.16	gold quality
tonsil	UBERON:0002372	74.71	gold quality
sural nerve	UBERON:0015488	73.88	gold quality
skeletal muscle tissue	UBERON:0001134	71.21	gold quality
calcaneal tendon	UBERON:0003701	69.23	gold quality
uterine cervix	UBERON:0000002	68.87	gold quality
liver	UBERON:0002107	66.72	gold quality
bone marrow cell	CL:0002092	64.87	silver quality
corpus callosum	UBERON:0002336	63.97	gold quality
bone marrow	UBERON:0002371	62.63	silver quality
blood	UBERON:0000178	62.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.04	gold quality
kidney	UBERON:0002113	59.10	gold quality
urinary bladder	UBERON:0001255	58.38	gold quality
endometrium	UBERON:0001295	56.03	silver quality
ectocervix	UBERON:0012249	55.71	gold quality
adrenal gland	UBERON:0002369	55.27	gold quality
monocyte	CL:0000576	54.96	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.77	gold quality
lung	UBERON:0002048	54.19	gold quality
islet of Langerhans	UBERON:0000006	53.83	gold quality
muscle of leg	UBERON:0001383	53.21	gold quality
placenta	UBERON:0001987	51.96	gold quality
stomach	UBERON:0000945	51.80	gold quality
prefrontal cortex	UBERON:0000451	51.58	gold quality
thoracic mammary gland	UBERON:0005200	50.70	gold quality
myometrium	UBERON:0001296	50.24	gold quality
intestine	UBERON:0000160	49.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.